{
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  "capturedAt": "2026-10-27T11:18:42.867Z",
  "sha256": "c9f348224e08be638bf248664dc8b38c9bb447af376db7b86c62d7187b289c14",
  "work": {
    "id": "TAP-RDN-0003",
    "type": "RDN",
    "kind": "note",
    "key": "van-dongen-2003",
    "locale": "en",
    "path": "/research/van-dongen-2003/",
    "title": "TAP reading note: The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation",
    "description": "Repeated sleep restriction produced cumulative cognitive performance deficits that subjective sleepiness did not fully track.",
    "rights": "© The Allostasis Project. All rights reserved. Reproduction or adaptation requires separate permission, subject to applicable legal exceptions.",
    "version": "0.2",
    "updatedAt": "2026-10-27",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-27",
      "version": "0.2",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "TAP Research Agent / OpenAI Codex",
          "scope": "Bilingual editorial revision and consolidation of scope statements based on the published text.",
          "version": "0.2",
          "tasks": [
            "Bilingual editing",
            "Scope and citation-position comparison"
          ]
        }
      },
      "revisions": [
        {
          "date": "2026-10-27",
          "version": "0.2",
          "description": "Reframed scope in terms of study design, population, outcomes and observation window."
        }
      ]
    },
    "original": {
      "id": "van-dongen-2003",
      "title": "The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation",
      "authors": "Hans P. A. Van Dongen · Greg Maislin · Janet M. Mullington · David F. Dinges",
      "journal": "Sleep",
      "year": "2003",
      "url": "https://pubmed.ncbi.nlm.nih.gov/12683469/",
      "doi": "10.1093/sleep/26.2.117",
      "pmid": "12683469"
    },
    "references": [
      {
        "id": "van-dongen-2003",
        "title": "The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation",
        "authors": "Hans P. A. Van Dongen · Greg Maislin · Janet M. Mullington · David F. Dinges",
        "journal": "Sleep",
        "year": "2003",
        "url": "https://pubmed.ncbi.nlm.nih.gov/12683469/",
        "doi": "10.1093/sleep/26.2.117",
        "pmid": "12683469"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "What the study found",
        "paragraphs": [
          "Repeated sleep restriction produced cumulative cognitive performance deficits that subjective sleepiness did not fully track."
        ]
      },
      {
        "id": "limits",
        "title": "Scope & limitations",
        "paragraphs": [
          "48 healthy adults aged 21–38; experiments included 14 nights of restricted time in bed",
          "The laboratory design controlled sleep opportunities and measurement conditions. Findings demonstrate cumulative performance changes; individual recovery timing and everyday settings require separate observation."
        ]
      },
      {
        "id": "sample",
        "title": "Population & sample",
        "paragraphs": [
          "48 healthy adults aged 21–38; experiments included 14 nights of restricted time in bed"
        ]
      },
      {
        "id": "exposure",
        "title": "Exposure or intervention",
        "paragraphs": [
          "4, 6 or 8 hours in bed per night; a separate total-deprivation experiment"
        ]
      },
      {
        "id": "outcomes",
        "title": "Outcomes",
        "paragraphs": [
          "Cognitive performance, subjective sleepiness and sleep physiology"
        ]
      },
      {
        "id": "duration",
        "title": "Time frame",
        "paragraphs": [
          "14 nights of restriction or 3 nights without sleep; 3 baseline and 3 recovery days in each experiment"
        ]
      },
      {
        "id": "funding",
        "title": "Research funding",
        "paragraphs": [
          "Not yet verified against the full text."
        ]
      },
      {
        "id": "conflicts",
        "title": "Research conflicts of interest",
        "paragraphs": [
          "Not yet verified against the full text."
        ]
      },
      {
        "id": "basis",
        "title": "Reading scope",
        "paragraphs": [
          "This selected reading note links to the original source. Bibliographic details have been checked; full-text verification is incomplete."
        ]
      }
    ]
  }
}