{
  "schemaVersion": 1,
  "capturedAt": "2026-10-27T11:18:42.890Z",
  "sha256": "2f275e0f4e64cba5b77fa517cb1717e637bb9bceb8aef6a196b98131b95ca92d",
  "work": {
    "id": "TAP-RDN-0003",
    "type": "RDN",
    "kind": "note",
    "key": "van-dongen-2003",
    "locale": "zh",
    "path": "/zh/research/van-dongen-2003/",
    "title": "TAP 导读: The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation",
    "description": "连续限制睡眠机会后，认知表现的下降会累积，而主观困倦没有同步反映全部变化。",
    "rights": "© The Allostasis Project。保留所有权利。除法律允许的例外外，转载或改编需另行授权。",
    "version": "0.2",
    "updatedAt": "2026-10-27",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-27",
      "version": "0.2",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "TAP Research Agent / OpenAI Codex",
          "scope": "基于已发布正文的中英文表达修订与范围说明整理。",
          "version": "0.2",
          "tasks": [
            "中英文编辑",
            "范围说明与引用位置对照"
          ]
        }
      },
      "revisions": [
        {
          "date": "2026-10-27",
          "version": "0.2",
          "description": "按研究设计、人群、结局与观察窗口重写适用范围说明。"
        }
      ]
    },
    "original": {
      "id": "van-dongen-2003",
      "title": "The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation",
      "authors": "Hans P. A. Van Dongen · Greg Maislin · Janet M. Mullington · David F. Dinges",
      "journal": "Sleep",
      "year": "2003",
      "url": "https://pubmed.ncbi.nlm.nih.gov/12683469/",
      "doi": "10.1093/sleep/26.2.117",
      "pmid": "12683469"
    },
    "references": [
      {
        "id": "van-dongen-2003",
        "title": "The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation",
        "authors": "Hans P. A. Van Dongen · Greg Maislin · Janet M. Mullington · David F. Dinges",
        "journal": "Sleep",
        "year": "2003",
        "url": "https://pubmed.ncbi.nlm.nih.gov/12683469/",
        "doi": "10.1093/sleep/26.2.117",
        "pmid": "12683469"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "研究发现",
        "paragraphs": [
          "连续限制睡眠机会后，认知表现的下降会累积，而主观困倦没有同步反映全部变化。"
        ]
      },
      {
        "id": "limits",
        "title": "范围与局限",
        "paragraphs": [
          "48 名 21–38 岁健康成年人；包含连续 14 夜限制卧床时间的实验",
          "实验室设计控制了睡眠机会与测量条件。结果展示累积的表现变化，个体恢复时程与日常情境仍需单独观察。"
        ]
      },
      {
        "id": "sample",
        "title": "研究人群与样本",
        "paragraphs": [
          "48 名 21–38 岁健康成年人；包含连续 14 夜限制卧床时间的实验"
        ]
      },
      {
        "id": "exposure",
        "title": "暴露或干预",
        "paragraphs": [
          "每晚卧床 4、6 或 8 小时；另含完全睡眠剥夺实验"
        ]
      },
      {
        "id": "outcomes",
        "title": "观察结局",
        "paragraphs": [
          "认知表现、主观困倦与睡眠生理"
        ]
      },
      {
        "id": "duration",
        "title": "时间范围",
        "paragraphs": [
          "14 夜限制睡眠或 3 夜无睡眠；每项实验均有 3 天基线与 3 天恢复"
        ]
      },
      {
        "id": "funding",
        "title": "研究资金来源",
        "paragraphs": [
          "尚未根据全文核实。"
        ]
      },
      {
        "id": "conflicts",
        "title": "研究利益关系",
        "paragraphs": [
          "尚未根据全文核实。"
        ]
      },
      {
        "id": "basis",
        "title": "导读范围",
        "paragraphs": [
          "本导读连接原始来源，供专题阅读参考。引文信息已经核对；尚未完成全文核查。"
        ]
      }
    ]
  }
}