{
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  "capturedAt": "2026-10-29T10:31:13.700Z",
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  "work": {
    "id": "TAP-RDN-0003",
    "type": "RDN",
    "kind": "note",
    "key": "van-dongen-2003",
    "locale": "zh",
    "path": "/zh/research/van-dongen-2003/",
    "title": "TAP 导读: The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation",
    "description": "这篇研究比较反复限制睡眠与完全睡眠剥夺中的神经行为和睡眠生理变化。本条目前提供原文及勘误的检索入口；详细数值、模型公式与定量解释暂缓，等待核清2004年的正式勘误。",
    "rights": "© The Allostasis Project。保留所有权利。除法律允许的例外外，转载或改编需另行授权。",
    "version": "0.3",
    "updatedAt": "2026-10-29",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-29",
      "version": "0.3",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "OpenAI Codex",
          "scope": "Assisted source comparison, evidence extraction and bilingual research-note preparation. The materials consulted and unresolved scientific issues are specified in each note.",
          "version": "0.3",
          "tasks": [
            "Source comparison and evidence extraction",
            "Bilingual research-note drafting and editorial comparison"
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        }
      },
      "revisions": [
        {
          "date": "2026-10-27",
          "version": "0.2",
          "description": "按研究设计、人群、结局与观察窗口重写适用范围说明。"
        },
        {
          "date": "2026-10-29",
          "version": "0.3",
          "description": "补记2004年正式勘误；在更正内容核清前暂缓详细数值与模型解释。"
        }
      ]
    },
    "original": {
      "id": "van-dongen-2003",
      "title": "The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation",
      "authors": "Hans P. A. Van Dongen · Greg Maislin · Janet M. Mullington · David F. Dinges",
      "journal": "Sleep",
      "year": "2003",
      "url": "https://pubmed.ncbi.nlm.nih.gov/12683469/",
      "doi": "10.1093/sleep/26.2.117",
      "pmid": "12683469"
    },
    "references": [
      {
        "id": "van-dongen-2003",
        "title": "The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation",
        "authors": "Hans P. A. Van Dongen · Greg Maislin · Janet M. Mullington · David F. Dinges",
        "journal": "Sleep",
        "year": "2003",
        "url": "https://pubmed.ncbi.nlm.nih.gov/12683469/",
        "doi": "10.1093/sleep/26.2.117",
        "pmid": "12683469"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "研究发现",
        "paragraphs": [
          "这篇研究比较反复限制睡眠与完全睡眠剥夺中的神经行为和睡眠生理变化。本条目前提供原文及勘误的检索入口；详细数值、模型公式与定量解释暂缓，等待核清2004年的正式勘误。"
        ]
      },
      {
        "id": "limits",
        "title": "范围与局限",
        "paragraphs": [
          "健康成年人的受控实验；本版以书目与更正提示为主要范围。",
          "PubMed确认存在Sleep 2004;27(4):600勘误，但通知正文尚未取得。现有2003年PDF早于勘误，不能认定更正仅涉及排版或不影响数值，也不据其模型给出个人睡眠时长建议。"
        ]
      },
      {
        "id": "sample",
        "title": "研究人群与样本",
        "paragraphs": [
          "健康成年人的受控实验；本版以书目与更正提示为主要范围。"
        ]
      },
      {
        "id": "exposure",
        "title": "暴露或干预",
        "paragraphs": [
          "反复限制睡眠机会与完全睡眠剥夺，含基线和恢复观察。"
        ]
      },
      {
        "id": "outcomes",
        "title": "观察结局",
        "paragraphs": [
          "神经行为表现、主观困倦与睡眠生理；具体效应和模型参数等待更正核对。"
        ]
      },
      {
        "id": "duration",
        "title": "时间范围",
        "paragraphs": [
          "原研究为连续多夜实验；本版暂不提供定量恢复时程。"
        ]
      },
      {
        "id": "funding",
        "title": "研究资金来源",
        "paragraphs": [
          "尚未根据全文核实。"
        ]
      },
      {
        "id": "conflicts",
        "title": "研究利益关系",
        "paragraphs": [
          "尚未根据全文核实。"
        ]
      },
      {
        "id": "basis",
        "title": "导读范围",
        "paragraphs": [
          "已查阅2003年原刊PDF及PubMed勘误关联；Sleep 2004;27(4):600的更正内容仍待取得。本版保持为带更正提示的文献入口。"
        ],
        "links": [
          {
            "label": "勘误题录；通知正文待核",
            "url": "https://pubmed.ncbi.nlm.nih.gov/12683469/"
          }
        ]
      }
    ]
  }
}