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  "capturedAt": "2026-09-14T08:27:22.729Z",
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  "work": {
    "id": "TAP-RDN-0005",
    "kind": "note",
    "key": "mcewen-2011",
    "locale": "zh",
    "path": "/zh/research/mcewen-2011/",
    "title": "TAP 导读: Stress- and Allostasis-Induced Brain Plasticity",
    "description": "讨论压力、适应过程与大脑可塑性的联系。",
    "rights": "© The Allostasis Project。保留所有权利。除法律允许的例外外，转载或改编需另行授权。",
    "version": "0.1",
    "updatedAt": "2026-09-14",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-09-14",
      "version": "0.1",
      "author": null,
      "reviewer": null,
      "revisions": []
    },
    "original": {
      "id": "mcewen-2011",
      "title": "Stress- and Allostasis-Induced Brain Plasticity",
      "authors": "Bruce S. McEwen · Peter J. Gianaros",
      "journal": "Annual Review of Medicine",
      "year": "2011",
      "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC4251716/",
      "doi": "10.1146/annurev-med-052209-100430",
      "pmid": "20707675"
    },
    "references": [
      {
        "id": "mcewen-2011",
        "title": "Stress- and Allostasis-Induced Brain Plasticity",
        "authors": "Bruce S. McEwen · Peter J. Gianaros",
        "journal": "Annual Review of Medicine",
        "year": "2011",
        "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC4251716/",
        "doi": "10.1146/annurev-med-052209-100430",
        "pmid": "20707675"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "研究发现",
        "paragraphs": [
          "讨论压力、适应过程与大脑可塑性的联系。"
        ]
      },
      {
        "id": "limits",
        "title": "范围与局限",
        "paragraphs": [
          "综合人与动物研究；无单一试验样本",
          "证据涵盖不同物种与研究设计；机制发现不能直接外推为特定人体干预效果。"
        ]
      },
      {
        "id": "sample",
        "title": "研究人群与样本",
        "paragraphs": [
          "综合人与动物研究；无单一试验样本"
        ]
      },
      {
        "id": "exposure",
        "title": "暴露或干预",
        "paragraphs": [
          "压力与动态适应；人与动物文献"
        ]
      },
      {
        "id": "outcomes",
        "title": "观察结局",
        "paragraphs": [
          "大脑可塑性与压力相关调节"
        ]
      },
      {
        "id": "duration",
        "title": "时间范围",
        "paragraphs": [
          "没有统一观察时间"
        ]
      },
      {
        "id": "funding",
        "title": "研究资金来源",
        "paragraphs": [
          "尚未根据全文核实。"
        ]
      },
      {
        "id": "conflicts",
        "title": "研究利益关系",
        "paragraphs": [
          "尚未根据全文核实。"
        ]
      },
      {
        "id": "basis",
        "title": "导读范围",
        "paragraphs": [
          "本导读连接原始来源，供专题阅读参考。引文信息已经核对；尚未完成全文核查。"
        ]
      }
    ],
    "type": "RDN"
  }
}