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  "sha256": "410b3efd15ad554b61851bf5deeaf5501f7317ddda500c68079cb717bfbabc56",
  "work": {
    "id": "TAP-RDN-0016",
    "type": "RDN",
    "kind": "note",
    "key": "brosschot-2006",
    "locale": "en",
    "path": "/research/brosschot-2006/",
    "title": "TAP reading note: The perseverative cognition hypothesis: a review of worry, prolonged stress-related physiological activation, and health",
    "description": "The perseverative-cognition hypothesis proposes that worry, rumination, anticipation and post-event processing can extend physiological activation beyond a stressor. It motivates measuring the event, repetitive thought and subsequent physiology together. The paper also notes that direct evidence for objective disease outcomes was limited.",
    "rights": "© The Allostasis Project. All rights reserved. Reproduction or adaptation requires separate permission, subject to applicable legal exceptions.",
    "version": "0.3",
    "updatedAt": "2026-10-29",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-29",
      "version": "0.3",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "OpenAI Codex",
          "scope": "Assisted source comparison, evidence extraction and bilingual research-note preparation. The materials consulted and unresolved scientific issues are specified in each note.",
          "version": "0.3",
          "tasks": [
            "Source comparison and evidence extraction",
            "Bilingual research-note drafting and editorial comparison"
          ]
        }
      },
      "revisions": [
        {
          "date": "2026-10-27",
          "version": "0.2",
          "description": "Reframed scope in terms of study design, population, outcomes and observation window."
        },
        {
          "date": "2026-10-29",
          "version": "0.3",
          "description": "Added the author-text definition of perseverative cognition and limitations of the disease evidence."
        }
      ]
    },
    "original": {
      "id": "brosschot-2006",
      "title": "The perseverative cognition hypothesis: a review of worry, prolonged stress-related physiological activation, and health",
      "authors": "Brosschot JF · Gerin W · Thayer JF",
      "journal": "Journal of psychosomatic research",
      "year": "2006",
      "url": "https://doi.org/10.1016/j.jpsychores.2005.06.074",
      "doi": "10.1016/j.jpsychores.2005.06.074",
      "pmid": "16439263"
    },
    "references": [
      {
        "id": "brosschot-2006",
        "title": "The perseverative cognition hypothesis: a review of worry, prolonged stress-related physiological activation, and health",
        "authors": "Brosschot JF · Gerin W · Thayer JF",
        "journal": "Journal of psychosomatic research",
        "year": "2006",
        "url": "https://doi.org/10.1016/j.jpsychores.2005.06.074",
        "doi": "10.1016/j.jpsychores.2005.06.074",
        "pmid": "16439263"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "What the study found",
        "paragraphs": [
          "The perseverative-cognition hypothesis proposes that worry, rumination, anticipation and post-event processing can extend physiological activation beyond a stressor. It motivates measuring the event, repetitive thought and subsequent physiology together. The paper also notes that direct evidence for objective disease outcomes was limited."
        ]
      },
      {
        "id": "limits",
        "title": "Scope & limitations",
        "paragraphs": [
          "Literature on worry, rumination and anticipatory stress; no new trial sample.",
          "State and trait measures differ across this narrative review, which provides no single pooled effect. Perseverative cognition, general negative affect and causal pathways to chronic disease require separate tests."
        ]
      },
      {
        "id": "sample",
        "title": "Population & sample",
        "paragraphs": [
          "Literature on worry, rumination and anticipatory stress; no new trial sample."
        ]
      },
      {
        "id": "exposure",
        "title": "Exposure or intervention",
        "paragraphs": [
          "Repetitive cognition before and after stressors and prolonged autonomic or endocrine activation."
        ]
      },
      {
        "id": "outcomes",
        "title": "Outcomes",
        "paragraphs": [
          "Physiological activation and possible health consequences, with disease evidence considered separately."
        ]
      },
      {
        "id": "duration",
        "title": "Time frame",
        "paragraphs": [
          "Anticipatory, post-event and longer-term processes; no uniform observation window."
        ]
      },
      {
        "id": "funding",
        "title": "Research funding",
        "paragraphs": [
          "Not yet verified against the full text."
        ]
      },
      {
        "id": "conflicts",
        "title": "Research conflicts of interest",
        "paragraphs": [
          "Not yet verified against the full text."
        ]
      },
      {
        "id": "basis",
        "title": "Reading scope",
        "paragraphs": [
          "Author-uploaded web full text: definition, central argument, disease evidence and conclusion. Tables, all references and separate disclosures have not been fully checked."
        ],
        "links": [
          {
            "label": "Author-uploaded full-text record",
            "url": "https://www.researchgate.net/publication/7334916_The_perseverative_cognition_hypothesis_A_review_of_worry_prolonged_stress-related_physiological_activation_and_health"
          }
        ]
      }
    ]
  }
}