{
  "schemaVersion": 1,
  "capturedAt": "2026-10-29T10:31:13.704Z",
  "sha256": "1303158de0a0f7cfd14f431dd0f187fe9d2815b0224e02487b84ee39b315aebd",
  "work": {
    "id": "TAP-RDN-0018",
    "type": "RDN",
    "kind": "note",
    "key": "billman-2013",
    "locale": "zh",
    "path": "/zh/research/billman-2013/",
    "title": "TAP 导读: The LF/HF ratio does not accurately measure cardiac sympatho-vagal balance",
    "description": "Billman检视把LF/HF解释为心脏交感—迷走平衡所需的假设。LF并非纯交感信号，HF也受呼吸和机械因素影响；交感与副交感活动不总是互反或线性变化，因此相同比值可能对应不同生理过程。",
    "rights": "© The Allostasis Project。保留所有权利。除法律允许的例外外，转载或改编需另行授权。",
    "version": "0.3",
    "updatedAt": "2026-10-29",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-29",
      "version": "0.3",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "OpenAI Codex",
          "scope": "Assisted source comparison, evidence extraction and bilingual research-note preparation. The materials consulted and unresolved scientific issues are specified in each note.",
          "version": "0.3",
          "tasks": [
            "Source comparison and evidence extraction",
            "Bilingual research-note drafting and editorial comparison"
          ]
        }
      },
      "revisions": [
        {
          "date": "2026-10-27",
          "version": "0.2",
          "description": "按研究设计、人群、结局与观察窗口重写适用范围说明。"
        },
        {
          "date": "2026-10-29",
          "version": "0.3",
          "description": "补充LF/HF的生理假设及该批评适用的具体范围。"
        }
      ]
    },
    "original": {
      "id": "billman-2013",
      "title": "The LF/HF ratio does not accurately measure cardiac sympatho-vagal balance",
      "authors": "George E. Billman",
      "journal": "Frontiers in Physiology",
      "year": "2013",
      "url": "https://doi.org/10.3389/fphys.2013.00026",
      "doi": "10.3389/fphys.2013.00026",
      "pmid": "23431279"
    },
    "references": [
      {
        "id": "billman-2013",
        "title": "The LF/HF ratio does not accurately measure cardiac sympatho-vagal balance",
        "authors": "George E. Billman",
        "journal": "Frontiers in Physiology",
        "year": "2013",
        "url": "https://doi.org/10.3389/fphys.2013.00026",
        "doi": "10.3389/fphys.2013.00026",
        "pmid": "23431279"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "研究发现",
        "paragraphs": [
          "Billman检视把LF/HF解释为心脏交感—迷走平衡所需的假设。LF并非纯交感信号，HF也受呼吸和机械因素影响；交感与副交感活动不总是互反或线性变化，因此相同比值可能对应不同生理过程。"
        ]
      },
      {
        "id": "limits",
        "title": "范围与局限",
        "paragraphs": [
          "既有生理实验与数学论证；无新患者队列。",
          "批评针对LF/HF的这一特定解释，不能扩大为所有HRV指标都没有信息。其他指标仍须结合各自生理依据、呼吸、心率及记录条件评价。"
        ]
      },
      {
        "id": "sample",
        "title": "研究人群与样本",
        "paragraphs": [
          "既有生理实验与数学论证；无新患者队列。"
        ]
      },
      {
        "id": "exposure",
        "title": "暴露或干预",
        "paragraphs": [
          "比较LF、HF及其比值的解释假设，涉及阻断、去神经和呼吸研究。"
        ]
      },
      {
        "id": "outcomes",
        "title": "观察结局",
        "paragraphs": [
          "自主神经解释的机制与假设；没有新的诊断准确率估计。"
        ]
      },
      {
        "id": "duration",
        "title": "时间范围",
        "paragraphs": [
          "生理实验和模型例证的时间尺度不同，无统一随访。"
        ]
      },
      {
        "id": "funding",
        "title": "研究资金来源",
        "paragraphs": [
          "尚未根据全文核实。"
        ]
      },
      {
        "id": "conflicts",
        "title": "研究利益关系",
        "paragraphs": [
          "尚未根据全文核实。"
        ]
      },
      {
        "id": "basis",
        "title": "导读范围",
        "paragraphs": [
          "全文四项解释假设、呼吸和心率影响及结论；全部原始实验引用尚未逐项追溯。"
        ],
        "links": [
          {
            "label": "PubMed Central全文",
            "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC3576706/"
          }
        ]
      }
    ]
  }
}