{
  "schemaVersion": 1,
  "capturedAt": "2026-10-29T10:31:13.704Z",
  "sha256": "d3ee721a572ab4abc69844b6812db65026d7a5f2a515fbe198ba8af17fdba0b3",
  "work": {
    "id": "TAP-RDN-0026",
    "type": "RDN",
    "kind": "note",
    "key": "pejovic-2013",
    "locale": "zh",
    "path": "/zh/research/pejovic-2013/",
    "title": "TAP 导读: Effects of recovery sleep after one work week of mild sleep restriction on interleukin-6 and cortisol secretion and daytime sleepiness and performance",
    "description": "轻度睡眠限制后，不同指标的恢复并不同步。两夜延长睡眠后，IL-6与基线的差异不显著，困倦和疲劳改善，但持续注意表现未恢复。限制阶段的24小时皮质醇本身也未显著升高，不能把恢复后的下降解释为所有应激指标共同归位。",
    "rights": "© The Allostasis Project。保留所有权利。除法律允许的例外外，转载或改编需另行授权。",
    "version": "0.3",
    "updatedAt": "2026-10-29",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-29",
      "version": "0.3",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "OpenAI Codex",
          "scope": "Assisted source comparison, evidence extraction and bilingual research-note preparation. The materials consulted and unresolved scientific issues are specified in each note.",
          "version": "0.3",
          "tasks": [
            "Source comparison and evidence extraction",
            "Bilingual research-note drafting and editorial comparison"
          ]
        }
      },
      "revisions": [
        {
          "date": "2026-10-27",
          "version": "0.2",
          "description": "按研究设计、人群、结局与观察窗口重写适用范围说明。"
        },
        {
          "date": "2026-10-29",
          "version": "0.3",
          "description": "补充固定顺序设计、IL-6比较及限制期皮质醇未显著升高的结果。"
        }
      ]
    },
    "original": {
      "id": "pejovic-2013",
      "title": "Effects of recovery sleep after one work week of mild sleep restriction on interleukin-6 and cortisol secretion and daytime sleepiness and performance",
      "authors": "Slobodanka Pejovic · Maria Basta · Alexandros N. Vgontzas · Ilia Kritikou · Michele L. Shaffer · Marina Tsaoussoglou · David Stiffler · Zacharias Stefanakis · Edward O. Bixler · George P. Chrousos",
      "journal": "American Journal of Physiology-Endocrinology and Metabolism",
      "year": "2013",
      "url": "https://doi.org/10.1152/ajpendo.00301.2013",
      "doi": "10.1152/ajpendo.00301.2013",
      "pmid": "23941878"
    },
    "references": [
      {
        "id": "pejovic-2013",
        "title": "Effects of recovery sleep after one work week of mild sleep restriction on interleukin-6 and cortisol secretion and daytime sleepiness and performance",
        "authors": "Slobodanka Pejovic · Maria Basta · Alexandros N. Vgontzas · Ilia Kritikou · Michele L. Shaffer · Marina Tsaoussoglou · David Stiffler · Zacharias Stefanakis · Edward O. Bixler · George P. Chrousos",
        "journal": "American Journal of Physiology-Endocrinology and Metabolism",
        "year": "2013",
        "url": "https://doi.org/10.1152/ajpendo.00301.2013",
        "doi": "10.1152/ajpendo.00301.2013",
        "pmid": "23941878"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "研究发现",
        "paragraphs": [
          "轻度睡眠限制后，不同指标的恢复并不同步。两夜延长睡眠后，IL-6与基线的差异不显著，困倦和疲劳改善，但持续注意表现未恢复。限制阶段的24小时皮质醇本身也未显著升高，不能把恢复后的下降解释为所有应激指标共同归位。"
        ]
      },
      {
        "id": "limits",
        "title": "范围与局限",
        "paragraphs": [
          "30名健康成年人，16男、14女，按固定顺序进行自身前后比较。",
          "没有外部对照，固定顺序、练习效应、提前起床与日间活动可能混杂。未发现与基线显著不同，不等于经过等效性检验；结果只适用于该观察窗和相应结局。"
        ]
      },
      {
        "id": "sample",
        "title": "研究人群与样本",
        "paragraphs": [
          "30名健康成年人，16男、14女，按固定顺序进行自身前后比较。"
        ]
      },
      {
        "id": "exposure",
        "title": "暴露或干预",
        "paragraphs": [
          "4夜8小时、6夜6小时、3夜10小时卧床；在5夜限制和2夜恢复后采集关键指标。"
        ]
      },
      {
        "id": "outcomes",
        "title": "观察结局",
        "paragraphs": [
          "IL-6、24小时皮质醇、困倦、疲劳与警觉表现；恢复后IL-6相对基线差.02±.34 pg/mL，P=.94。"
        ]
      },
      {
        "id": "duration",
        "title": "时间范围",
        "paragraphs": [
          "13夜实验，重点比较限制后与两夜恢复后的状态。"
        ]
      },
      {
        "id": "funding",
        "title": "研究资金来源",
        "paragraphs": [
          "尚未根据全文核实。"
        ]
      },
      {
        "id": "conflicts",
        "title": "研究利益关系",
        "paragraphs": [
          "尚未根据全文核实。"
        ]
      },
      {
        "id": "basis",
        "title": "导读范围",
        "paragraphs": [
          "PMC网页全文的流程、采血、结果与讨论；独立对照、节律对齐和更长恢复期需要其他研究。"
        ],
        "links": [
          {
            "label": "PubMed Central全文",
            "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC3798707/"
          }
        ]
      }
    ]
  }
}