{
  "schemaVersion": 1,
  "capturedAt": "2026-09-20T06:32:55.709Z",
  "sha256": "7d455e0181be3d048df6e53fb60f1445438d2e4046ba6b32b8da37c5903790dd",
  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "beese-2025",
    "id": "TAP-RDN-0035",
    "locale": "zh",
    "path": "/zh/research/beese-2025/",
    "title": "TAP 导读: Allostatic (over)Load Measurement: Workflow and repository",
    "description": "这项工作通过工作流与代码仓库，使二次数据中五指标适应负荷指数的构建过程可以被检查。预印本介绍工作流；TAP 另行使用 NHANES 2015–2016 数据，检验参照人群与计分规则的敏感性。",
    "rights": "© The Allostasis Project。保留所有权利。除法律允许的例外外，转载或改编需另行授权。",
    "version": "1.0",
    "updatedAt": "2026-09-20",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-09-20",
      "version": "1.0",
      "byline": "team",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "TAP Research Agent / Codex",
          "scope": "Computational checks are reported separately from human scientific or methods review.",
          "version": "1.0",
          "tasks": [
            "Source inspection",
            "Independent analysis implementation",
            "Numerical cross-checking",
            "Writing and translation"
          ]
        }
      },
      "revisions": []
    },
    "original": {
      "id": "beese-2025",
      "title": "Allostatic (over)Load Measurement: Workflow and repository",
      "authors": "Shawna Beese · J. Cross · D. Rice · T. L. DeJong",
      "journal": "medRxiv (preprint)",
      "year": "2025",
      "url": "https://doi.org/10.1101/2025.07.31.25332519",
      "doi": "10.1101/2025.07.31.25332519"
    },
    "references": [
      {
        "id": "beese-2025",
        "title": "Allostatic (over)Load Measurement: Workflow and repository",
        "authors": "Shawna Beese · J. Cross · D. Rice · T. L. DeJong",
        "journal": "medRxiv (preprint)",
        "year": "2025",
        "url": "https://doi.org/10.1101/2025.07.31.25332519",
        "doi": "10.1101/2025.07.31.25332519"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "研究发现",
        "paragraphs": [
          "这项工作通过工作流与代码仓库，使二次数据中五指标适应负荷指数的构建过程可以被检查。预印本介绍工作流；TAP 另行使用 NHANES 2015–2016 数据，检验参照人群与计分规则的敏感性。"
        ]
      },
      {
        "id": "limits",
        "title": "范围与局限",
        "paragraphs": [
          "涵盖 All of Us、HRS 与 NHANES 的二次数据工作流；它们是不同数据来源，并非合并后的统一验证队列。",
          "这是预印本，不是已经验证的个人压力或复原力工具。能够算出指数，不代表建立了通用诊断阈值、每日恢复敏感性或预测表现。代码在 2025 年预印本之后继续更新，因此应分别标识论文与代码版本。"
        ]
      },
      {
        "id": "sample",
        "title": "研究人群与样本",
        "paragraphs": [
          "源工作流涵盖三类数据资源。配套 TAP 方法案例评价 NHANES 2015–2016 中 3,152 名五项齐全的 40 岁以上成年人；这是 TAP 的分析样本，不是源论文的总样本量。"
        ]
      },
      {
        "id": "exposure",
        "title": "暴露或干预",
        "paragraphs": [
          "五项指标：CRP、HbA1c、HDL 胆固醇、心率或调查脉搏、腰高比。实现涉及数据组装、阈值选择及风险标记求和。"
        ]
      },
      {
        "id": "outcomes",
        "title": "观察结局",
        "paragraphs": [
          "计算得到的适应负荷指数。工作流可复核，与针对疾病、死亡或个人恢复结局的验证，是不同问题。"
        ]
      },
      {
        "id": "duration",
        "title": "时间范围",
        "paragraphs": [
          "预印本第 1 版：2025 年 8 月 1 日。所查代码：固定提交 2bbb624dd01cec5c54b778d3cd2df4ada582c989（2026 年更新）。TAP 自身分析仅使用 NHANES 2015–2016 单周期。"
        ]
      },
      {
        "id": "funding",
        "title": "研究资金来源",
        "paragraphs": [
          "本导读未独立提取源论文资金信息，请查阅原预印本声明。"
        ]
      },
      {
        "id": "conflicts",
        "title": "研究利益关系",
        "paragraphs": [
          "TAP 未独立审计源作者的利益关系。引用不代表源作者认可 TAP 或 Resilio。"
        ]
      },
      {
        "id": "basis",
        "title": "导读范围",
        "paragraphs": [
          "预印本摘要及此前检查的工作流正文、固定仓库源码；2026 年 9 月 20 日通过 medRxiv 再次核对元数据，接口未返回期刊发表链接。TAP 独立重建 NHANES 周期逻辑并执行原生 R 核验，没有运行源作者完整笔记本或复现 All of Us/HRS。新增结果见关联的 TAP 方法案例。"
        ]
      }
    ]
  }
}