{
  "schemaVersion": 1,
  "capturedAt": "2026-10-27T11:18:42.868Z",
  "sha256": "120213d7ba9eaf143ba1661e71dabe9bf93e17cacf90fb7b553e671e7c692b89",
  "work": {
    "kind": "note",
    "type": "RDN",
    "key": "tieland-2012",
    "id": "TAP-RDN-0038",
    "locale": "en",
    "path": "/research/tieland-2012/",
    "title": "TAP reading note: Protein supplementation improves physical performance in frail elderly people: a randomized, double-blind, placebo-controlled trial",
    "description": "Physical performance improved with protein supplementation; muscle mass did not.",
    "rights": "© The Allostasis Project. All rights reserved. Reproduction or adaptation requires separate permission, subject to applicable legal exceptions.",
    "version": "1.1",
    "updatedAt": "2026-10-27",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-27",
      "version": "1.1",
      "byline": "team",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "TAP Research Agent / OpenAI Codex",
          "scope": "Bilingual editorial revision and consolidation of scope statements based on the published text.",
          "version": "1.1",
          "tasks": [
            "Bilingual editing",
            "Scope and citation-position comparison"
          ]
        }
      },
      "revisions": [
        {
          "date": "2026-10-27",
          "version": "1.1",
          "description": "Reframed scope in terms of study design, population, outcomes and observation window."
        }
      ]
    },
    "original": {
      "id": "tieland-2012",
      "title": "Protein supplementation improves physical performance in frail elderly people: a randomized, double-blind, placebo-controlled trial",
      "authors": "Michael Tieland et al.",
      "journal": "Journal of the American Medical Directors Association",
      "year": "2012",
      "url": "https://doi.org/10.1016/j.jamda.2012.07.005",
      "doi": "10.1016/j.jamda.2012.07.005",
      "pmid": "22889730"
    },
    "references": [
      {
        "id": "tieland-2012",
        "title": "Protein supplementation improves physical performance in frail elderly people: a randomized, double-blind, placebo-controlled trial",
        "authors": "Michael Tieland et al.",
        "journal": "Journal of the American Medical Directors Association",
        "year": "2012",
        "url": "https://doi.org/10.1016/j.jamda.2012.07.005",
        "doi": "10.1016/j.jamda.2012.07.005",
        "pmid": "22889730"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "What the study found",
        "paragraphs": [
          "Physical performance improved with protein supplementation; muscle mass did not."
        ]
      },
      {
        "id": "limits",
        "title": "Scope & limitations",
        "paragraphs": [
          "65 frail older adults.",
          "Findings come from an intervention trial in frail older adults. Physical performance and muscle mass are distinct outcomes; extension to other age or functional groups requires corresponding studies."
        ]
      },
      {
        "id": "sample",
        "title": "Population & sample",
        "paragraphs": [
          "65 frail older adults."
        ]
      },
      {
        "id": "exposure",
        "title": "Exposure or intervention",
        "paragraphs": [
          "Protein supplementation versus placebo."
        ]
      },
      {
        "id": "outcomes",
        "title": "Outcomes",
        "paragraphs": [
          "Muscle mass, strength and physical performance."
        ]
      },
      {
        "id": "duration",
        "title": "Time frame",
        "paragraphs": [
          "24 weeks."
        ]
      },
      {
        "id": "funding",
        "title": "Research funding",
        "paragraphs": [
          "Not extracted from the abstract."
        ]
      },
      {
        "id": "conflicts",
        "title": "Research conflicts of interest",
        "paragraphs": [
          "Not extracted from the abstract."
        ]
      },
      {
        "id": "basis",
        "title": "Reading scope",
        "paragraphs": [
          "PubMed abstract and bibliographic record."
        ]
      }
    ]
  }
}