{
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  "capturedAt": "2026-10-28T03:31:47.147Z",
  "sha256": "335a6d060bb9bf8cbdd98493f510c2860e49ff69ab4952e11b37d2f7410880d5",
  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "li-2026",
    "id": "TAP-RDN-0043",
    "locale": "en",
    "path": "/research/li-2026/",
    "title": "TAP reading note: Acute sleep rebound following sleep restriction is associated with reduced mortality risk",
    "description": "Mortality associations differed across restriction/rebound patterns; rebound groups were not significantly different from regular sleep.",
    "rights": "© The Allostasis Project. All rights reserved. Reproduction or adaptation requires separate permission, subject to applicable legal exceptions.",
    "version": "1.0",
    "updatedAt": "2026-10-28",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-28",
      "version": "1.0",
      "byline": "team",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "TAP Research Agent / OpenAI Codex",
          "scope": "Assisted literature research, bilingual writing and explanatory visual preparation. Source access is specified in the reading notes.",
          "version": "1.0",
          "tasks": [
            "Source retrieval and comparison",
            "Bilingual drafting and illustration design"
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        }
      },
      "revisions": []
    },
    "original": {
      "id": "li-2026",
      "title": "Acute sleep rebound following sleep restriction is associated with reduced mortality risk",
      "authors": "Xiaoyu Li · Manrui Zhang · Zhenyu Li · Shengkui Zhang · Suzanne M. Bertisch · Tianyi Huang · Martin K. Rutter · Susan Redline",
      "journal": "Nature Communications",
      "year": "2026",
      "url": "https://doi.org/10.1038/s41467-026-72461-1",
      "doi": "10.1038/s41467-026-72461-1"
    },
    "references": [
      {
        "id": "li-2026",
        "title": "Acute sleep rebound following sleep restriction is associated with reduced mortality risk",
        "authors": "Xiaoyu Li · Manrui Zhang · Zhenyu Li · Shengkui Zhang · Suzanne M. Bertisch · Tianyi Huang · Martin K. Rutter · Susan Redline",
        "journal": "Nature Communications",
        "year": "2026",
        "url": "https://doi.org/10.1038/s41467-026-72461-1",
        "doi": "10.1038/s41467-026-72461-1"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "What the study found",
        "paragraphs": [
          "Mortality associations differed across restriction/rebound patterns; rebound groups were not significantly different from regular sleep."
        ]
      },
      {
        "id": "limits",
        "title": "Scope & limitations",
        "paragraphs": [
          "85,618 UK Biobank participants; replication in 4,586 NHANES participants.",
          "Observational; rebound is not specifically weekend sleep. Non-significance does not establish equivalence or causation."
        ]
      },
      {
        "id": "sample",
        "title": "Population & sample",
        "paragraphs": [
          "85,618 UK Biobank participants; replication in 4,586 NHANES participants."
        ]
      },
      {
        "id": "exposure",
        "title": "Exposure or intervention",
        "paragraphs": [
          "Accelerometer-derived restriction and subsequent rebound."
        ]
      },
      {
        "id": "outcomes",
        "title": "Outcomes",
        "paragraphs": [
          "Mortality associations."
        ]
      },
      {
        "id": "duration",
        "title": "Time frame",
        "paragraphs": [
          "Median UK Biobank follow-up: 8.0 years."
        ]
      },
      {
        "id": "funding",
        "title": "Research funding",
        "paragraphs": [
          "No specific study funding statement was identified in the consulted main text."
        ]
      },
      {
        "id": "conflicts",
        "title": "Research conflicts of interest",
        "paragraphs": [
          "M. K. Rutter: Eli Lilly consulting and modest GSK holdings, reported as unrelated. S. Redline: Eli Lilly consulting, Sleep Health editorship, unpaid National Sleep Foundation and Alliance of Sleep Apnea Partners board roles. Others declared no competing interests."
        ]
      },
      {
        "id": "basis",
        "title": "Reading scope",
        "paragraphs": [
          "Publisher full text: methods, results and declarations."
        ]
      }
    ]
  }
}
