{
  "schemaVersion": 1,
  "capturedAt": "2026-10-28T03:31:47.147Z",
  "sha256": "f8d68eb3c3176b75ad1b7c724372f67aaa48bdd2b73bcb68bf52b25b54c3d2b3",
  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "oxfeldt-2023",
    "id": "TAP-RDN-0045",
    "locale": "en",
    "path": "/research/oxfeldt-2023/",
    "title": "TAP reading note: Low energy availability reduces myofibrillar and sarcoplasmic muscle protein synthesis in trained females",
    "description": "Lower energy availability reduced integrated muscle protein synthesis.",
    "rights": "© The Allostasis Project. All rights reserved. Reproduction or adaptation requires separate permission, subject to applicable legal exceptions.",
    "version": "1.0",
    "updatedAt": "2026-10-28",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-28",
      "version": "1.0",
      "byline": "team",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "TAP Research Agent / OpenAI Codex",
          "scope": "Assisted literature research, bilingual writing and explanatory visual preparation. Source access is specified in the reading notes.",
          "version": "1.0",
          "tasks": [
            "Source retrieval and comparison",
            "Bilingual drafting and illustration design"
          ]
        }
      },
      "revisions": []
    },
    "original": {
      "id": "oxfeldt-2023",
      "title": "Low energy availability reduces myofibrillar and sarcoplasmic muscle protein synthesis in trained females",
      "authors": "Mikkel Oxfeldt · Stuart M. Phillips · Ole Emil Andersen · Frank Ted Johansen · Maj Bangshaab · Jeyanthini Risikesan · James McKendry · Anna Katarina Melin · Mette Hansen",
      "journal": "The Journal of Physiology",
      "year": "2023",
      "url": "https://doi.org/10.1113/JP284967",
      "doi": "10.1113/JP284967",
      "pmid": "37329147"
    },
    "references": [
      {
        "id": "oxfeldt-2023",
        "title": "Low energy availability reduces myofibrillar and sarcoplasmic muscle protein synthesis in trained females",
        "authors": "Mikkel Oxfeldt · Stuart M. Phillips · Ole Emil Andersen · Frank Ted Johansen · Maj Bangshaab · Jeyanthini Risikesan · James McKendry · Anna Katarina Melin · Mette Hansen",
        "journal": "The Journal of Physiology",
        "year": "2023",
        "url": "https://doi.org/10.1113/JP284967",
        "doi": "10.1113/JP284967",
        "pmid": "37329147"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "What the study found",
        "paragraphs": [
          "Lower energy availability reduced integrated muscle protein synthesis."
        ]
      },
      {
        "id": "limits",
        "title": "Scope & limitations",
        "paragraphs": [
          "30 trained, eumenorrheic women randomized.",
          "Short, controlled exposure in trained women; protein synthesis is not a whole-body recovery outcome."
        ]
      },
      {
        "id": "sample",
        "title": "Population & sample",
        "paragraphs": [
          "30 trained, eumenorrheic women randomized."
        ]
      },
      {
        "id": "exposure",
        "title": "Exposure or intervention",
        "paragraphs": [
          "Provided diets with lower versus adequate energy availability; standardized training and matched protein provision."
        ]
      },
      {
        "id": "outcomes",
        "title": "Outcomes",
        "paragraphs": [
          "Integrated myofibrillar and sarcoplasmic protein synthesis."
        ]
      },
      {
        "id": "duration",
        "title": "Time frame",
        "paragraphs": [
          "Ten intervention days after a five-day run-in."
        ]
      },
      {
        "id": "funding",
        "title": "Research funding",
        "paragraphs": [
          "Aarhus University Faculty of Health, Danish Ministry of Culture and Team Danmark; J. McKendry held a CIHR postdoctoral fellowship."
        ]
      },
      {
        "id": "conflicts",
        "title": "Research conflicts of interest",
        "paragraphs": [
          "S. M. Phillips disclosed grants/contracts from US National Dairy Council, CIHR, Dairy Farmers of Canada, Roquette Freres, Ontario Centre of Innovation, Nestle Health Sciences, Myos, NSERC, Friesland Campina and US NIH; Nestle personal fees and Enhanced Recovery non-financial support outside this work; Exerkine-licensed patents without reported financial gains."
        ]
      },
      {
        "id": "basis",
        "title": "Reading scope",
        "paragraphs": [
          "Publisher full text and Aarhus University repository PDF, including final-page disclosures."
        ]
      }
    ]
  }
}
