{
  "schemaVersion": 1,
  "capturedAt": "2026-10-28T03:31:47.147Z",
  "sha256": "6afe1ccda448ecb40138cea6158700d1f0f01bb2cb819adb6e358edeb982c3da",
  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "jeppesen-2024",
    "id": "TAP-RDN-0046",
    "locale": "en",
    "path": "/research/jeppesen-2024/",
    "title": "TAP reading note: Low energy availability increases immune cell formation of reactive oxygen species and impairs exercise performance in female endurance athletes",
    "description": "Low availability impaired performance; the time-trial impairment persisted after three refueling days.",
    "rights": "© The Allostasis Project. All rights reserved. Reproduction or adaptation requires separate permission, subject to applicable legal exceptions.",
    "version": "1.0",
    "updatedAt": "2026-10-28",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-28",
      "version": "1.0",
      "byline": "team",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "TAP Research Agent / OpenAI Codex",
          "scope": "Assisted literature research, bilingual writing and explanatory visual preparation. Source access is specified in the reading notes.",
          "version": "1.0",
          "tasks": [
            "Source retrieval and comparison",
            "Bilingual drafting and illustration design"
          ]
        }
      },
      "revisions": []
    },
    "original": {
      "id": "jeppesen-2024",
      "title": "Low energy availability increases immune cell formation of reactive oxygen species and impairs exercise performance in female endurance athletes",
      "authors": "Jan S. Jeppesen · Hannah G. Caldwell · Lone O. Lossius · Anna K. Melin · Lasse Gliemann · Jens Bangsbo · Ylva Hellsten",
      "journal": "Redox Biology",
      "year": "2024",
      "url": "https://doi.org/10.1016/j.redox.2024.103250",
      "doi": "10.1016/j.redox.2024.103250",
      "pmid": "38936255"
    },
    "references": [
      {
        "id": "jeppesen-2024",
        "title": "Low energy availability increases immune cell formation of reactive oxygen species and impairs exercise performance in female endurance athletes",
        "authors": "Jan S. Jeppesen · Hannah G. Caldwell · Lone O. Lossius · Anna K. Melin · Lasse Gliemann · Jens Bangsbo · Ylva Hellsten",
        "journal": "Redox Biology",
        "year": "2024",
        "url": "https://doi.org/10.1016/j.redox.2024.103250",
        "doi": "10.1016/j.redox.2024.103250",
        "pmid": "38936255"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "What the study found",
        "paragraphs": [
          "Low availability impaired performance; the time-trial impairment persisted after three refueling days."
        ]
      },
      {
        "id": "limits",
        "title": "Scope & limitations",
        "paragraphs": [
          "12 female endurance athletes; randomized crossover.",
          "Small athlete sample; energy and nutrient availability changed together. Immune-cell measures do not establish clinical illness."
        ]
      },
      {
        "id": "sample",
        "title": "Population & sample",
        "paragraphs": [
          "12 female endurance athletes; randomized crossover."
        ]
      },
      {
        "id": "exposure",
        "title": "Exposure or intervention",
        "paragraphs": [
          "Low versus optimal energy availability, followed by refueling."
        ]
      },
      {
        "id": "outcomes",
        "title": "Outcomes",
        "paragraphs": [
          "Cycling performance and immune-cell/physiological measures."
        ]
      },
      {
        "id": "duration",
        "title": "Time frame",
        "paragraphs": [
          "Fourteen days per dietary condition, then three refueling days."
        ]
      },
      {
        "id": "funding",
        "title": "Research funding",
        "paragraphs": [
          "Danish Ministry of Culture sports-research funding; Frimodt-Heineke Fonden; Novo Nordisk Foundation support for Team Denmark’s training-strategies and competition-preparation network."
        ]
      },
      {
        "id": "conflicts",
        "title": "Research conflicts of interest",
        "paragraphs": [
          "Authors declared no known competing financial interests or personal relationships affecting the work."
        ]
      },
      {
        "id": "basis",
        "title": "Reading scope",
        "paragraphs": [
          "PMC full text: protocol, performance results, funding and declarations."
        ]
      }
    ]
  }
}
