{
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  "capturedAt": "2026-10-29T10:31:13.634Z",
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  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "windred-2024",
    "id": "TAP-RDN-0061",
    "locale": "en",
    "path": "/research/windred-2024/",
    "title": "TAP reading note: Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study",
    "description": "More regular sleep was associated with lower all-cause mortality. In models including regularity alone, the highest versus lowest quintile HR changed from .52 (95% CI .45–.60) with minimal adjustment to .70 (.59–.83) with full adjustment; including sleep duration yielded .74 (.62–.89). This motivates attention to regularity but does not establish the effect of changing sleep schedules.",
    "rights": "© The Allostasis Project. All rights reserved. Reproduction or adaptation requires separate permission, subject to applicable legal exceptions.",
    "version": "1.0",
    "updatedAt": "2026-10-29",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-29",
      "version": "1.0",
      "byline": "team",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "OpenAI Codex",
          "scope": "Assisted source comparison, evidence extraction and bilingual research-note preparation. The materials consulted and unresolved scientific issues are specified in each note.",
          "version": "1.0",
          "tasks": [
            "Source comparison and evidence extraction",
            "Bilingual research-note drafting and editorial comparison"
          ]
        }
      },
      "revisions": [
        {
          "date": "2026-10-29",
          "version": "1.0",
          "description": "Added regularity/mortality evidence with separate model samples, adjustment estimates and the unresolved total-sample discrepancy."
        }
      ]
    },
    "original": {
      "id": "windred-2024",
      "title": "Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study",
      "authors": "Windred DP · Burns AC · Lane JM · Saxena R · Rutter MK · Cain SW · Phillips AJK",
      "journal": "SLEEP",
      "year": "2024",
      "url": "https://doi.org/10.1093/sleep/zsad253",
      "doi": "10.1093/sleep/zsad253",
      "pmid": "37738616"
    },
    "references": [
      {
        "id": "windred-2024",
        "title": "Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study",
        "authors": "Windred DP · Burns AC · Lane JM · Saxena R · Rutter MK · Cain SW · Phillips AJK",
        "journal": "SLEEP",
        "year": "2024",
        "url": "https://doi.org/10.1093/sleep/zsad253",
        "doi": "10.1093/sleep/zsad253",
        "pmid": "37738616"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "What the study found",
        "paragraphs": [
          "More regular sleep was associated with lower all-cause mortality. In models including regularity alone, the highest versus lowest quintile HR changed from .52 (95% CI .45–.60) with minimal adjustment to .70 (.59–.83) with full adjustment; including sleep duration yielded .74 (.62–.89). This motivates attention to regularity but does not establish the effect of changing sleep schedules."
        ]
      },
      {
        "id": "limits",
        "title": "Scope & limitations",
        "paragraphs": [
          "UK Biobank accelerometry cohort with 1,859 deaths. The abstract/discussion gives 60,977 people, while the characteristics section gives 60,997; this discrepancy remains unresolved. Minimal/full models included 60,780/46,721.",
          "Observational design, one-week measurement, a relatively homogeneous middle/older-age sample and residual confounding constrain inference. Full adjustment also reduced the sample, so attenuation cannot be attributed entirely to covariates. Associations do not establish calibrated individual prediction."
        ]
      },
      {
        "id": "sample",
        "title": "Population & sample",
        "paragraphs": [
          "UK Biobank accelerometry cohort with 1,859 deaths. The abstract/discussion gives 60,977 people, while the characteristics section gives 60,997; this discrepancy remains unresolved. Minimal/full models included 60,780/46,721."
        ]
      },
      {
        "id": "exposure",
        "title": "Exposure or intervention",
        "paragraphs": [
          "Seven-day accelerometer estimates of sleep regularity and duration, grouped into quintiles and modelled separately and together."
        ]
      },
      {
        "id": "outcomes",
        "title": "Outcomes",
        "paragraphs": [
          "All-cause and cause-specific mortality, with model-specific denominators and adjustment sets."
        ]
      },
      {
        "id": "duration",
        "title": "Time frame",
        "paragraphs": [
          "Seven-day sleep measurement and mean mortality follow-up of 6.30 years."
        ]
      },
      {
        "id": "funding",
        "title": "Research funding",
        "paragraphs": [
          "A. J. K. Phillips and S. W. Cain disclosed Delos and Versalux research support; Cain also disclosed Beacon Lighting support. All public funding awards have not been fully checked."
        ]
      },
      {
        "id": "conflicts",
        "title": "Research conflicts of interest",
        "paragraphs": [
          "Phillips and Cain disclosed cofounder/management relationships with Circadian Health Innovations; Cain also disclosed Dyson consulting."
        ]
      },
      {
        "id": "basis",
        "title": "Reading scope",
        "paragraphs": [
          "Full-text sample, regularity definition, models, mortality results and limitations. Total-sample discrepancies, covariate missingness and all supplements remain to be checked."
        ],
        "links": [
          {
            "label": "Full text in PubMed Central",
            "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC10782501/"
          }
        ]
      }
    ]
  }
}