{
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  "capturedAt": "2026-10-29T10:31:13.717Z",
  "sha256": "d83a8bc58b714f44b83386eb398c76b8be1c9b3317ce81c2fd89e01fb074d640",
  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "windred-2024",
    "id": "TAP-RDN-0061",
    "locale": "zh",
    "path": "/zh/research/windred-2024/",
    "title": "TAP 导读: Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study",
    "description": "较规律的睡眠与较低全因死亡风险相关。仅纳入睡眠规律性指标的模型中，最高相对最低五分位组HR从最小调整的.52（95%CI .45—.60）变为充分调整的.70（.59—.83）；共同纳入睡眠时长后为.74（.62—.89）。这支持关注规律性，但并未证明改变作息就能产生相同风险下降。",
    "rights": "© The Allostasis Project。保留所有权利。除法律允许的例外外，转载或改编需另行授权。",
    "version": "1.0",
    "updatedAt": "2026-10-29",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-29",
      "version": "1.0",
      "byline": "team",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "OpenAI Codex",
          "scope": "Assisted source comparison, evidence extraction and bilingual research-note preparation. The materials consulted and unresolved scientific issues are specified in each note.",
          "version": "1.0",
          "tasks": [
            "Source comparison and evidence extraction",
            "Bilingual research-note drafting and editorial comparison"
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        }
      },
      "revisions": [
        {
          "date": "2026-10-29",
          "version": "1.0",
          "description": "新增规律性与死亡关联，分别列出模型分母、调整结果及总体人数差异。"
        }
      ]
    },
    "original": {
      "id": "windred-2024",
      "title": "Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study",
      "authors": "Windred DP · Burns AC · Lane JM · Saxena R · Rutter MK · Cain SW · Phillips AJK",
      "journal": "SLEEP",
      "year": "2024",
      "url": "https://doi.org/10.1093/sleep/zsad253",
      "doi": "10.1093/sleep/zsad253",
      "pmid": "37738616"
    },
    "references": [
      {
        "id": "windred-2024",
        "title": "Sleep regularity is a stronger predictor of mortality risk than sleep duration: A prospective cohort study",
        "authors": "Windred DP · Burns AC · Lane JM · Saxena R · Rutter MK · Cain SW · Phillips AJK",
        "journal": "SLEEP",
        "year": "2024",
        "url": "https://doi.org/10.1093/sleep/zsad253",
        "doi": "10.1093/sleep/zsad253",
        "pmid": "37738616"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "研究发现",
        "paragraphs": [
          "较规律的睡眠与较低全因死亡风险相关。仅纳入睡眠规律性指标的模型中，最高相对最低五分位组HR从最小调整的.52（95%CI .45—.60）变为充分调整的.70（.59—.83）；共同纳入睡眠时长后为.74（.62—.89）。这支持关注规律性，但并未证明改变作息就能产生相同风险下降。"
        ]
      },
      {
        "id": "limits",
        "title": "范围与局限",
        "paragraphs": [
          "UK Biobank加速度计队列，1,859例死亡。摘要/讨论写60,977人，特征段写60,997人，差异待核；最小与充分调整模型实际为60,780和46,721人。",
          "观察性设计、单周测量、较同质的中老年样本和剩余混杂限制外推。充分调整时样本也减少，效应减弱不能全部归因于协变量调整。规律性与时长的关联不等于个人预测工具已经校准。"
        ]
      },
      {
        "id": "sample",
        "title": "研究人群与样本",
        "paragraphs": [
          "UK Biobank加速度计队列，1,859例死亡。摘要/讨论写60,977人，特征段写60,997人，差异待核；最小与充分调整模型实际为60,780和46,721人。"
        ]
      },
      {
        "id": "exposure",
        "title": "暴露或干预",
        "paragraphs": [
          "七日加速度计估计睡眠规律性指数和睡眠时长，分五组分别及共同建模。"
        ]
      },
      {
        "id": "outcomes",
        "title": "观察结局",
        "paragraphs": [
          "全因及分原因死亡；不同模型的分母和调整方案分别解释。"
        ]
      },
      {
        "id": "duration",
        "title": "时间范围",
        "paragraphs": [
          "七日睡眠测量，平均死亡随访6.30年。"
        ]
      },
      {
        "id": "funding",
        "title": "研究资金来源",
        "paragraphs": [
          "A. J. K. Phillips和S. W. Cain披露Delos与Versalux研究支持；Cain另有Beacon Lighting研究支持。全部公共资助项目尚未核全。"
        ]
      },
      {
        "id": "conflicts",
        "title": "研究利益关系",
        "paragraphs": [
          "Phillips和Cain披露Circadian Health Innovations共同创办或管理关系；Cain另报Dyson顾问关系。"
        ]
      },
      {
        "id": "basis",
        "title": "导读范围",
        "paragraphs": [
          "全文样本、规律性定义、模型、死亡结果与局限；总体人数差异、协变量缺失及全部附件仍待核对。"
        ],
        "links": [
          {
            "label": "PubMed Central全文",
            "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC10782501/"
          }
        ]
      }
    ]
  }
}