{
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  "capturedAt": "2026-10-29T10:31:13.709Z",
  "sha256": "f0e6cc304441160abdfe83b0824005134165b68389779008d45551c6d5d18ef2",
  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "scheffer-2018",
    "id": "TAP-RDN-0064",
    "locale": "zh",
    "path": "/zh/research/scheffer-2018/",
    "title": "TAP 导读: Quantifying resilience of humans and other animals",
    "description": "论文提出从动态波动中研究复原力：恢复变慢可能伴随方差、时间自相关或子系统相关的变化。这些动态指标提供了可检验的思路，但图中的模拟和被引研究结果不构成本论文新增的人体临床验证。",
    "rights": "© The Allostasis Project。保留所有权利。除法律允许的例外外，转载或改编需另行授权。",
    "version": "1.0",
    "updatedAt": "2026-10-29",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-10-29",
      "version": "1.0",
      "byline": "team",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "OpenAI Codex",
          "scope": "Assisted source comparison, evidence extraction and bilingual research-note preparation. The materials consulted and unresolved scientific issues are specified in each note.",
          "version": "1.0",
          "tasks": [
            "Source comparison and evidence extraction",
            "Bilingual research-note drafting and editorial comparison"
          ]
        }
      },
      "revisions": [
        {
          "date": "2026-10-29",
          "version": "1.0",
          "description": "新增动态复原力理论，明确临界减速假设与临床验证范围。"
        }
      ]
    },
    "original": {
      "id": "scheffer-2018",
      "title": "Quantifying resilience of humans and other animals",
      "authors": "Scheffer M · Bolhuis JE · Borsboom D · Buchman TG · Gijzel SMW · Goulson D · Kammenga JE · Kemp B · van de Leemput IA · Levin S · Martin CM · Melis RJF · van Nes EH · Romero LM · Olde Rikkert MGM",
      "journal": "Proceedings of the National Academy of Sciences",
      "year": "2018",
      "url": "https://doi.org/10.1073/pnas.1810630115",
      "doi": "10.1073/pnas.1810630115",
      "pmid": "30373844"
    },
    "references": [
      {
        "id": "scheffer-2018",
        "title": "Quantifying resilience of humans and other animals",
        "authors": "Scheffer M · Bolhuis JE · Borsboom D · Buchman TG · Gijzel SMW · Goulson D · Kammenga JE · Kemp B · van de Leemput IA · Levin S · Martin CM · Melis RJF · van Nes EH · Romero LM · Olde Rikkert MGM",
        "journal": "Proceedings of the National Academy of Sciences",
        "year": "2018",
        "url": "https://doi.org/10.1073/pnas.1810630115",
        "doi": "10.1073/pnas.1810630115",
        "pmid": "30373844"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "研究发现",
        "paragraphs": [
          "论文提出从动态波动中研究复原力：恢复变慢可能伴随方差、时间自相关或子系统相关的变化。这些动态指标提供了可检验的思路，但图中的模拟和被引研究结果不构成本论文新增的人体临床验证。"
        ]
      },
      {
        "id": "limits",
        "title": "范围与局限",
        "paragraphs": [
          "人类、动物和复杂系统文献及模型例证；无新的统一患者队列。",
          "临界减速依赖近稳态和扰动结构等假设，并不适合所有周期、混沌或突变系统。测量噪声、外界扰动和治疗变化也能改变同样指标，不能把任何高自相关都解释为复原力下降。"
        ]
      },
      {
        "id": "sample",
        "title": "研究人群与样本",
        "paragraphs": [
          "人类、动物和复杂系统文献及模型例证；无新的统一患者队列。"
        ]
      },
      {
        "id": "exposure",
        "title": "暴露或干预",
        "paragraphs": [
          "动态恢复率、时间自相关、方差及子系统交叉相关的理论与跨领域比较。"
        ]
      },
      {
        "id": "outcomes",
        "title": "观察结局",
        "paragraphs": [
          "动态复原力指标的候选含义与应用条件；没有统一诊断性能估计。"
        ]
      },
      {
        "id": "duration",
        "title": "时间范围",
        "paragraphs": [
          "跨越不同采样频率和恢复时间尺度；需要先定义具体系统与扰动。"
        ]
      },
      {
        "id": "funding",
        "title": "研究资金来源",
        "paragraphs": [
          "所取得正文未列独立资助段，资助信息仍未核实。"
        ]
      },
      {
        "id": "conflicts",
        "title": "研究利益关系",
        "paragraphs": [
          "作者声明无利益冲突。"
        ]
      },
      {
        "id": "basis",
        "title": "导读范围",
        "paragraphs": [
          "正文各部分及图1—3图注已通读；补充表S1/S2与所引用的人体前瞻研究仍待核读。"
        ],
        "links": [
          {
            "label": "PubMed Central全文",
            "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC6255191/"
          }
        ]
      }
    ]
  }
}