{
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  "capturedAt": "2026-11-13T05:44:15.585Z",
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  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "casuso-2025",
    "id": "TAP-RDN-0082",
    "locale": "zh",
    "path": "/zh/research/casuso-2025/",
    "title": "TAP 导读: Does Protein Ingestion Timing Affect Exercise-Induced Adaptations? A Systematic Review with Meta-Analysis",
    "description": "直接比较训练前与训练后摄入蛋白质，未发现去脂体重（标准化均差−0.08，95%置信区间−0.398至0.244）或胸推力量（0.07，−0.248至0.395）的明确差异。腿推力量出现有利于训练前摄入的信号，但仅来自两项研究。",
    "rights": "© The Allostasis Project。保留所有权利。除法律允许的例外外，转载或改编需另行授权。",
    "version": "1.0",
    "updatedAt": "2026-11-13",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
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      "reviewedVersion": null,
      "updatedAt": "2026-11-13",
      "version": "1.0",
      "byline": "team",
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      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "OpenAI Codex",
          "scope": "基于来源进行证据综合、写作与翻译；实际查阅材料及获取范围见各文献导读。",
          "version": "1.0",
          "tasks": [
            "Literature comparison and evidence extraction",
            "Bilingual explanatory writing and source-linked tables"
          ]
        }
      },
      "revisions": []
    },
    "original": {
      "id": "casuso-2025",
      "title": "Does Protein Ingestion Timing Affect Exercise-Induced Adaptations? A Systematic Review with Meta-Analysis",
      "authors": "Rafael A. Casuso; Lennert Goossens",
      "journal": "Nutrients",
      "year": "2025",
      "url": "https://doi.org/10.3390/nu17132070",
      "doi": "10.3390/nu17132070",
      "pmid": "40647175"
    },
    "references": [
      {
        "id": "casuso-2025",
        "title": "Does Protein Ingestion Timing Affect Exercise-Induced Adaptations? A Systematic Review with Meta-Analysis",
        "authors": "Rafael A. Casuso; Lennert Goossens",
        "journal": "Nutrients",
        "year": "2025",
        "url": "https://doi.org/10.3390/nu17132070",
        "doi": "10.3390/nu17132070",
        "pmid": "40647175"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "研究发现",
        "paragraphs": [
          "直接比较训练前与训练后摄入蛋白质，未发现去脂体重（标准化均差−0.08，95%置信区间−0.398至0.244）或胸推力量（0.07，−0.248至0.395）的明确差异。腿推力量出现有利于训练前摄入的信号，但仅来自两项研究。"
        ]
      },
      {
        "id": "limits",
        "title": "范围与局限",
        "paragraphs": [
          "6份报告对应5项随机研究，包含有训练经历的年轻人及未经训练的老年人，其中一项涉及2型糖尿病人群。",
          "作者将去脂体重及胸推证据确定性评为低，腿推及肌肉厚度评为极低。腿推估计为标准化均差0.70（0.005–1.388），p=.048；胸推与腿推的亚组差异未达显著（p=.07）。膳食控制程度不一，一项研究报告蛋白摄入存在差异。未见显著差异不等于证实等效。"
        ]
      },
      {
        "id": "sample",
        "title": "研究人群与样本",
        "paragraphs": [
          "6份报告对应5项随机研究，包含有训练经历的年轻人及未经训练的老年人，其中一项涉及2型糖尿病人群。"
        ]
      },
      {
        "id": "exposure",
        "title": "暴露或干预",
        "paragraphs": [
          "将参与者随机分配到多次抗阻训练前或后摄入蛋白质；多数安排接近训练时点，一项比较使用至少训练后2小时的安排。"
        ]
      },
      {
        "id": "outcomes",
        "title": "观察结局",
        "paragraphs": [
          "去脂体重、力量、脂肪量及肌肉厚度。"
        ]
      },
      {
        "id": "duration",
        "title": "时间范围",
        "paragraphs": [
          "纳入干预持续6–16周；数据库检索截至2024年1月15日。"
        ]
      },
      {
        "id": "funding",
        "title": "研究资金来源",
        "paragraphs": [
          "作者报告未接受外部资助。"
        ]
      },
      {
        "id": "conflicts",
        "title": "研究利益关系",
        "paragraphs": [
          "作者声明不存在利益冲突。"
        ]
      },
      {
        "id": "basis",
        "title": "导读范围",
        "paragraphs": [
          "查阅PMC全文的方法、研究特征表、合并结果、GRADE讨论及声明；未独立核查补充文件或各试验数据集。"
        ],
        "links": [
          {
            "label": "PubMed Central 全文",
            "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC12250900/"
          }
        ]
      }
    ]
  }
}