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  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "askow-2025",
    "id": "TAP-RDN-0084",
    "locale": "en",
    "path": "/research/askow-2025/",
    "title": "TAP reading note: Impact of Vegan Diets on Resistance Exercise-Mediated Myofibrillar Protein Synthesis in Healthy Young Males and Females: A Randomized Controlled Trial",
    "description": "The abstract reports no significant difference in integrated myofibrillar protein synthesis between the tested vegan/omnivorous diets or balanced/unbalanced protein distributions over nine days. This supplies a useful counterpoint to single-day meal-distribution experiments.",
    "rights": "© The Allostasis Project. All rights reserved. Reproduction or adaptation requires separate permission, subject to applicable legal exceptions.",
    "version": "1.0",
    "updatedAt": "2026-11-13",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
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      "reviewedVersion": null,
      "updatedAt": "2026-11-13",
      "version": "1.0",
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      "workflow": {
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          "scope": "Source-based synthesis, drafting and translation. Consulted materials and access limits are described in the reading notes.",
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            "Literature comparison and evidence extraction",
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    "original": {
      "id": "askow-2025",
      "title": "Impact of Vegan Diets on Resistance Exercise-Mediated Myofibrillar Protein Synthesis in Healthy Young Males and Females: A Randomized Controlled Trial",
      "authors": "Andrew T. Askow et al.",
      "journal": "Medicine & Science in Sports & Exercise",
      "year": "2025",
      "url": "https://doi.org/10.1249/MSS.0000000000003725",
      "doi": "10.1249/MSS.0000000000003725",
      "pmid": "40197715"
    },
    "references": [
      {
        "id": "askow-2025",
        "title": "Impact of Vegan Diets on Resistance Exercise-Mediated Myofibrillar Protein Synthesis in Healthy Young Males and Females: A Randomized Controlled Trial",
        "authors": "Andrew T. Askow et al.",
        "journal": "Medicine & Science in Sports & Exercise",
        "year": "2025",
        "url": "https://doi.org/10.1249/MSS.0000000000003725",
        "doi": "10.1249/MSS.0000000000003725",
        "pmid": "40197715"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "What the study found",
        "paragraphs": [
          "The abstract reports no significant difference in integrated myofibrillar protein synthesis between the tested vegan/omnivorous diets or balanced/unbalanced protein distributions over nine days. This supplies a useful counterpoint to single-day meal-distribution experiments."
        ]
      },
      {
        "id": "limits",
        "title": "Scope & limitations",
        "paragraphs": [
          "40 healthy, physically active young adults: 28 men and 12 women; mean age 25 years.",
          "The available abstract supports the stated design and broad result, not a full appraisal of adherence, precision, adverse events or funding. A nonsignificant result is not an equivalence test, and nine-day synthesis is not long-term muscle growth."
        ]
      },
      {
        "id": "sample",
        "title": "Population & sample",
        "paragraphs": [
          "40 healthy, physically active young adults: 28 men and 12 women; mean age 25 years."
        ]
      },
      {
        "id": "exposure",
        "title": "Exposure or intervention",
        "paragraphs": [
          "Weight-maintenance diets supplying 1.1–1.2 g/kg/day: omnivorous or vegan; three meals distributed 10/30/60% versus five occasions at 20% each; resistance exercise during the feeding period."
        ]
      },
      {
        "id": "outcomes",
        "title": "Outcomes",
        "paragraphs": [
          "Integrated myofibrillar protein synthesis assessed using deuterated water and muscle samples."
        ]
      },
      {
        "id": "duration",
        "title": "Time frame",
        "paragraphs": [
          "Nine days."
        ]
      },
      {
        "id": "funding",
        "title": "Research funding",
        "paragraphs": [
          "Not yet verified against the full text."
        ]
      },
      {
        "id": "conflicts",
        "title": "Research conflicts of interest",
        "paragraphs": [
          "Not yet verified against the full text."
        ]
      },
      {
        "id": "basis",
        "title": "Reading scope",
        "paragraphs": [
          "Publisher and PubMed abstract; the complete article was not available for this reading. Full methods, numerical group estimates and declarations remain to be checked."
        ],
        "links": [
          {
            "label": "Publisher abstract and article",
            "url": "https://doi.org/10.1249/MSS.0000000000003725"
          }
        ]
      }
    ]
  }
}