{
  "schemaVersion": 1,
  "capturedAt": "2026-11-13T08:41:22.492Z",
  "sha256": "28fdb6b7b81932ff0967128da9e1887dccd678fcc633cea143e98d7409a82563",
  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "man-2023",
    "id": "TAP-RDN-0090",
    "locale": "zh",
    "path": "/zh/research/man-2023/",
    "title": "TAP 导读: Multi-systemic evaluation of biological and emotional responses to the Trier Social Stress Test: A meta-analysis and systematic review",
    "description": "在选定的多系统 TSST 文献中，皮质醇和负性情绪较敏感。其他系统的支持不一致，或来自较少研究；结果取决于指标和时间比较。",
    "rights": "© The Allostasis Project。保留所有权利。除法律允许的例外外，转载或改编需另行授权。",
    "version": "1.0",
    "updatedAt": "2026-11-13",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-11-13",
      "version": "1.0",
      "byline": "team",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "OpenAI Codex",
          "scope": "基于来源进行研究、写作、翻译和图表整理；各导读分别记录实际查阅范围。",
          "version": "1.0",
          "tasks": [
            "Source comparison and quantitative interpretation",
            "Bilingual synthesis and accessible figures"
          ]
        }
      },
      "revisions": []
    },
    "original": {
      "id": "man-2023",
      "title": "Multi-systemic evaluation of biological and emotional responses to the Trier Social Stress Test: A meta-analysis and systematic review",
      "authors": "Man ISC, Shao R, Hou WK, Xin Li S, Liu FY, Lee M, Wing YK, Yau SY, Lee TMC",
      "journal": "Frontiers in neuroendocrinology",
      "year": "2023",
      "url": "https://doi.org/10.1016/j.yfrne.2022.101050",
      "doi": "10.1016/j.yfrne.2022.101050",
      "pmid": "36410619"
    },
    "references": [
      {
        "id": "man-2023",
        "title": "Multi-systemic evaluation of biological and emotional responses to the Trier Social Stress Test: A meta-analysis and systematic review",
        "authors": "Man ISC, Shao R, Hou WK, Xin Li S, Liu FY, Lee M, Wing YK, Yau SY, Lee TMC",
        "journal": "Frontiers in neuroendocrinology",
        "year": "2023",
        "url": "https://doi.org/10.1016/j.yfrne.2022.101050",
        "doi": "10.1016/j.yfrne.2022.101050",
        "pmid": "36410619"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "研究发现",
        "paragraphs": [
          "在选定的多系统 TSST 文献中，皮质醇和负性情绪较敏感。其他系统的支持不一致，或来自较少研究；结果取决于指标和时间比较。"
        ]
      },
      {
        "id": "limits",
        "title": "范围与局限",
        "paragraphs": [
          "综述纳入 61 项研究；58 项进入荟萃分析，共 2,459 名 18—65 岁健康参与者。",
          "多种指标的研究数量有限，人群以健康样本为主，时间比较也不同。敏感的反应指标不等于个人通用恢复阈值。"
        ]
      },
      {
        "id": "sample",
        "title": "研究人群与样本",
        "paragraphs": [
          "综述纳入 61 项研究；58 项进入荟萃分析，共 2,459 名 18—65 岁健康参与者。"
        ]
      },
      {
        "id": "exposure",
        "title": "暴露或干预",
        "paragraphs": [
          "TSST 暴露及生理、情绪测量。"
        ]
      },
      {
        "id": "outcomes",
        "title": "观察结局",
        "paragraphs": [
          "内分泌、生理、炎症与情绪变化，分别比较不同时间。"
        ]
      },
      {
        "id": "duration",
        "title": "时间范围",
        "paragraphs": [
          "纳入文献发表于 2005—2020 年；综述载于 2023 年期刊。"
        ]
      },
      {
        "id": "funding",
        "title": "研究资金来源",
        "paragraphs": [
          "香港研究资助局协作研究金 C7079-19GF（T. Lee）；粤港澳大湾区脑科学与类脑研究中心开放基金 2019007（R. Shao）。"
        ]
      },
      {
        "id": "conflicts",
        "title": "研究利益关系",
        "paragraphs": [
          "作者声明没有利益冲突。"
        ]
      },
      {
        "id": "basis",
        "title": "导读范围",
        "paragraphs": [
          "查阅大学存储库全文中的纳入标准、研究数、结局定义、结果与声明；没有独立复现补充分析。"
        ],
        "links": [
          {
            "label": "PubMed 书目与摘要",
            "url": "https://pubmed.ncbi.nlm.nih.gov/36410619/"
          },
          {
            "label": "大学托管全文",
            "url": "https://ira.lib.polyu.edu.hk/bitstream/10397/102286/1/1-s2.0-S0091302222000735-main.pdf"
          }
        ]
      }
    ]
  }
}