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  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "gu-2025",
    "id": "TAP-RDN-0091",
    "locale": "en",
    "path": "/research/gu-2025/",
    "title": "TAP reading note: Physiological and psychological responses to acute stress: A meta-analysis of the 171 studies of Trier Social Stress Test including 8452 healthy adults",
    "description": "Reported stress-reactivity estimates were g=1.25 (95% CI 1.13–1.38) for physiology and 0.93 (0.79–1.09) for psychology. Autonomic and HPA domains were 1.38 (1.23–1.54) and 1.04 (0.86–1.21).",
    "rights": "© The Allostasis Project. All rights reserved. Reproduction or adaptation requires separate permission, subject to applicable legal exceptions.",
    "version": "1.0",
    "updatedAt": "2026-11-13",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-11-13",
      "version": "1.0",
      "byline": "team",
      "author": null,
      "reviewer": null,
      "workflow": {
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          "system": "OpenAI Codex",
          "scope": "Source-based research, drafting, translation and figure preparation. Access scope is stated in each source note.",
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          "tasks": [
            "Source comparison and quantitative interpretation",
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      "revisions": []
    },
    "original": {
      "id": "gu-2025",
      "title": "Physiological and psychological responses to acute stress: A meta-analysis of the 171 studies of Trier Social Stress Test including 8452 healthy adults",
      "authors": "Gu H, Lei Y, Yao Y, Chen C, Liu C",
      "journal": "Psychoneuroendocrinology",
      "year": "2025",
      "url": "https://doi.org/10.1016/j.psyneuen.2025.107566",
      "doi": "10.1016/j.psyneuen.2025.107566",
      "pmid": "40834642"
    },
    "references": [
      {
        "id": "gu-2025",
        "title": "Physiological and psychological responses to acute stress: A meta-analysis of the 171 studies of Trier Social Stress Test including 8452 healthy adults",
        "authors": "Gu H, Lei Y, Yao Y, Chen C, Liu C",
        "journal": "Psychoneuroendocrinology",
        "year": "2025",
        "url": "https://doi.org/10.1016/j.psyneuen.2025.107566",
        "doi": "10.1016/j.psyneuen.2025.107566",
        "pmid": "40834642"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "What the study found",
        "paragraphs": [
          "Reported stress-reactivity estimates were g=1.25 (95% CI 1.13–1.38) for physiology and 0.93 (0.79–1.09) for psychology. Autonomic and HPA domains were 1.38 (1.23–1.54) and 1.04 (0.86–1.21)."
        ]
      },
      {
        "id": "limits",
        "title": "Scope & limitations",
        "paragraphs": [
          "171 TSST articles; 8,452 healthy adults.",
          "These are reactivity effects, not recovery speeds. Autonomic and HPA domains sit within physiology and cannot be counted as additional independent samples. Full pooling methods were not assessed for this note."
        ]
      },
      {
        "id": "sample",
        "title": "Population & sample",
        "paragraphs": [
          "171 TSST articles; 8,452 healthy adults."
        ]
      },
      {
        "id": "exposure",
        "title": "Exposure or intervention",
        "paragraphs": [
          "Acute psychosocial stress induced with the TSST."
        ]
      },
      {
        "id": "outcomes",
        "title": "Outcomes",
        "paragraphs": [
          "Standardized physiological and psychological stress responses."
        ]
      },
      {
        "id": "duration",
        "title": "Time frame",
        "paragraphs": [
          "Acute task comparisons; published in 2025."
        ]
      },
      {
        "id": "funding",
        "title": "Research funding",
        "paragraphs": [
          "Not yet verified against the full text."
        ]
      },
      {
        "id": "conflicts",
        "title": "Research conflicts of interest",
        "paragraphs": [
          "The declaration indexed in PubMed states no competing interests; full-text funding details have not been verified."
        ]
      },
      {
        "id": "basis",
        "title": "Reading scope",
        "paragraphs": [
          "PubMed bibliographic record and abstract. This note covers the question and reported findings; detailed methods, supplements and complete declarations were not assessed."
        ],
        "links": [
          {
            "label": "PubMed record and abstract",
            "url": "https://pubmed.ncbi.nlm.nih.gov/40834642/"
          }
        ]
      }
    ]
  }
}