{
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  "capturedAt": "2026-11-13T08:41:22.489Z",
  "sha256": "9cb79d5c64beeba3a4fd9f5e3864c3f3d125b57c6e45c5806d4de00e93bb5673",
  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "gideon-2020",
    "id": "TAP-RDN-0093",
    "locale": "zh",
    "path": "/zh/research/gideon-2020/",
    "title": "TAP 导读: Kinetics and Interrelations of the Renin Aldosterone Response to Acute Psychosocial Stress: A Neglected Stress System",
    "description": "表 2 中，压力组与自身基线的差异首次不显著分别出现在：肾素第 10 分钟、皮质醇第 60 分钟、唾液醛固酮第 90 分钟、血浆醛固酮第 180 分钟。肾素后来在第 30、60 分钟低于基线。",
    "rights": "© The Allostasis Project。保留所有权利。除法律允许的例外外，转载或改编需另行授权。",
    "version": "1.0",
    "updatedAt": "2026-11-13",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-11-13",
      "version": "1.0",
      "byline": "team",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "OpenAI Codex",
          "scope": "基于来源进行研究、写作、翻译和图表整理；各导读分别记录实际查阅范围。",
          "version": "1.0",
          "tasks": [
            "Source comparison and quantitative interpretation",
            "Bilingual synthesis and accessible figures"
          ]
        }
      },
      "revisions": []
    },
    "original": {
      "id": "gideon-2020",
      "title": "Kinetics and Interrelations of the Renin Aldosterone Response to Acute Psychosocial Stress: A Neglected Stress System",
      "authors": "Gideon A, Sauter C, Fieres J, Berger T, Renner B, Wirtz PH",
      "journal": "The Journal of clinical endocrinology and metabolism",
      "year": "2020",
      "url": "https://doi.org/10.1210/clinem/dgz190",
      "doi": "10.1210/clinem/dgz190",
      "pmid": "31711229"
    },
    "references": [
      {
        "id": "gideon-2020",
        "title": "Kinetics and Interrelations of the Renin Aldosterone Response to Acute Psychosocial Stress: A Neglected Stress System",
        "authors": "Gideon A, Sauter C, Fieres J, Berger T, Renner B, Wirtz PH",
        "journal": "The Journal of clinical endocrinology and metabolism",
        "year": "2020",
        "url": "https://doi.org/10.1210/clinem/dgz190",
        "doi": "10.1210/clinem/dgz190",
        "pmid": "31711229"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "研究发现",
        "paragraphs": [
          "表 2 中，压力组与自身基线的差异首次不显著分别出现在：肾素第 10 分钟、皮质醇第 60 分钟、唾液醛固酮第 90 分钟、血浆醛固酮第 180 分钟。肾素后来在第 30、60 分钟低于基线。"
        ]
      },
      {
        "id": "limits",
        "title": "范围与局限",
        "paragraphs": [
          "58 名健康年轻男性随机分到 TSST（34 人）或安慰 TSST（24 人）；唾液醛固酮子样本为 23/15 人。",
          "差异不显著不能证明等效、持续回归或每个人均恢复。离散采样不能确定准确转折时间；特定激素与年轻男性样本不能代表整个人的恢复。"
        ]
      },
      {
        "id": "sample",
        "title": "研究人群与样本",
        "paragraphs": [
          "58 名健康年轻男性随机分到 TSST（34 人）或安慰 TSST（24 人）；唾液醛固酮子样本为 23/15 人。"
        ]
      },
      {
        "id": "exposure",
        "title": "暴露或干预",
        "paragraphs": [
          "社会评价 TSST 与安慰任务对照。"
        ]
      },
      {
        "id": "outcomes",
        "title": "观察结局",
        "paragraphs": [
          "重复测量血浆肾素、血浆与唾液醛固酮，以及唾液皮质醇。"
        ]
      },
      {
        "id": "duration",
        "title": "时间范围",
        "paragraphs": [
          "任务结束后，醛固酮最长追踪至 180 分钟，肾素与皮质醇至 60 分钟。"
        ]
      },
      {
        "id": "funding",
        "title": "研究资金来源",
        "paragraphs": [
          "资助包括 DFG EXC 2117–422037984、瑞士国家科学基金 PP00P1_128565/1、German Scholars Organization GSO/CZS 2，以及 Stoll VITA 基金会，均授予 P. H. Wirtz。"
        ]
      },
      {
        "id": "conflicts",
        "title": "研究利益关系",
        "paragraphs": [
          "作者声明没有利益冲突。"
        ]
      },
      {
        "id": "basis",
        "title": "导读范围",
        "paragraphs": [
          "查阅已发表全文的人群分组、采样安排、表 2、结果与声明。图 1 展示离散统计比较，没有重建个体数据。"
        ],
        "links": [
          {
            "label": "PubMed 书目与摘要",
            "url": "https://pubmed.ncbi.nlm.nih.gov/31711229/"
          },
          {
            "label": "已发表全文",
            "url": "https://d-nb.info/1209879409/34"
          }
        ]
      }
    ]
  }
}
