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    "key": "pulopulos-2018",
    "id": "TAP-RDN-0095",
    "locale": "en",
    "path": "/research/pulopulos-2018/",
    "title": "TAP reading note: Association between changes in heart rate variability during the anticipation of a stressful situation and the stress-induced cortisol response",
    "description": "A larger anticipatory HRV decrease was associated with greater cortisol increase, but not cortisol recovery. Adjusted task-related HRV associations with cortisol increase or recovery were nonsignificant.",
    "rights": "© The Allostasis Project. All rights reserved. Reproduction or adaptation requires separate permission, subject to applicable legal exceptions.",
    "version": "1.0",
    "updatedAt": "2026-11-13",
    "editorial": {
      "contentType": "evidence-review",
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      "updatedAt": "2026-11-13",
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      "revisions": []
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    "original": {
      "id": "pulopulos-2018",
      "title": "Association between changes in heart rate variability during the anticipation of a stressful situation and the stress-induced cortisol response",
      "authors": "Pulopulos MM, Vanderhasselt MA, De Raedt R",
      "journal": "Psychoneuroendocrinology",
      "year": "2018",
      "url": "https://doi.org/10.1016/j.psyneuen.2018.05.004",
      "doi": "10.1016/j.psyneuen.2018.05.004",
      "pmid": "29758470"
    },
    "references": [
      {
        "id": "pulopulos-2018",
        "title": "Association between changes in heart rate variability during the anticipation of a stressful situation and the stress-induced cortisol response",
        "authors": "Pulopulos MM, Vanderhasselt MA, De Raedt R",
        "journal": "Psychoneuroendocrinology",
        "year": "2018",
        "url": "https://doi.org/10.1016/j.psyneuen.2018.05.004",
        "doi": "10.1016/j.psyneuen.2018.05.004",
        "pmid": "29758470"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "What the study found",
        "paragraphs": [
          "A larger anticipatory HRV decrease was associated with greater cortisol increase, but not cortisol recovery. Adjusted task-related HRV associations with cortisol increase or recovery were nonsignificant."
        ]
      },
      {
        "id": "limits",
        "title": "Scope & limitations",
        "paragraphs": [
          "171 healthy adults: 96 men and 75 women; mean age about 30.",
          "Association does not establish causal regulation. No matched non-stress control; time-of-day and participant factors matter. Peak-to-final decline is not demonstrated return to baseline."
        ]
      },
      {
        "id": "sample",
        "title": "Population & sample",
        "paragraphs": [
          "171 healthy adults: 96 men and 75 women; mean age about 30."
        ]
      },
      {
        "id": "exposure",
        "title": "Exposure or intervention",
        "paragraphs": [
          "Anticipation and performance of a laboratory social stress task."
        ]
      },
      {
        "id": "outcomes",
        "title": "Outcomes",
        "paragraphs": [
          "HRV change, cortisol increase and decline from observed cortisol peak to final sample."
        ]
      },
      {
        "id": "duration",
        "title": "Time frame",
        "paragraphs": [
          "Phase-specific recordings within one laboratory session."
        ]
      },
      {
        "id": "funding",
        "title": "Research funding",
        "paragraphs": [
          "Not yet verified against the full text."
        ]
      },
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        "id": "conflicts",
        "title": "Research conflicts of interest",
        "paragraphs": [
          "The PubMed-indexed authors’ statement reports no conflicts associated with the research."
        ]
      },
      {
        "id": "basis",
        "title": "Reading scope",
        "paragraphs": [
          "Accessible PMC author-manuscript methods and results, including adjusted analyses and the definition of recovery; PubMed bibliographic and competing-interest record. Supplementary and full funding details were not assessed."
        ],
        "links": [
          {
            "label": "PubMed record and abstract",
            "url": "https://pubmed.ncbi.nlm.nih.gov/29758470/"
          },
          {
            "label": "PMC author manuscript",
            "url": "https://pmc.ncbi.nlm.nih.gov/articles/PMC5967249/"
          }
        ]
      }
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}