{
  "schemaVersion": 1,
  "capturedAt": "2026-11-13T08:41:22.486Z",
  "sha256": "9d86cd8c054d8b64667af47d618316f955ce817f74fdf4c10e480702fc2afc1d",
  "work": {
    "type": "RDN",
    "kind": "note",
    "key": "steptoe-2016",
    "id": "TAP-RDN-0100",
    "locale": "zh",
    "path": "/zh/research/steptoe-2016/",
    "title": "TAP 导读: Blood Pressure and Fibrinogen Responses to Mental Stress as Predictors of Incident Hypertension over an 8-Year Period",
    "description": "恢复期收缩压最高与最低三分位组相比，后续高血压的调整后 OR 为 2.06（95% CI 1.19—3.57）。这是特定前瞻性关联，不是个人恢复截点。",
    "rights": "© The Allostasis Project。保留所有权利。除法律允许的例外外，转载或改编需另行授权。",
    "version": "1.0",
    "updatedAt": "2026-11-13",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
      "reviewedAt": null,
      "reviewedVersion": null,
      "updatedAt": "2026-11-13",
      "version": "1.0",
      "byline": "team",
      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "OpenAI Codex",
          "scope": "基于来源进行研究、写作、翻译和图表整理；各导读分别记录实际查阅范围。",
          "version": "1.0",
          "tasks": [
            "Source comparison and quantitative interpretation",
            "Bilingual synthesis and accessible figures"
          ]
        }
      },
      "revisions": []
    },
    "original": {
      "id": "steptoe-2016",
      "title": "Blood Pressure and Fibrinogen Responses to Mental Stress as Predictors of Incident Hypertension over an 8-Year Period",
      "authors": "Steptoe A, Kivimäki M, Lowe G, Rumley A, Hamer M",
      "journal": "Annals of behavioral medicine : a publication of the Society of Behavioral Medicine",
      "year": "2016",
      "url": "https://doi.org/10.1007/s12160-016-9817-5",
      "doi": "10.1007/s12160-016-9817-5",
      "pmid": "27401000"
    },
    "references": [
      {
        "id": "steptoe-2016",
        "title": "Blood Pressure and Fibrinogen Responses to Mental Stress as Predictors of Incident Hypertension over an 8-Year Period",
        "authors": "Steptoe A, Kivimäki M, Lowe G, Rumley A, Hamer M",
        "journal": "Annals of behavioral medicine : a publication of the Society of Behavioral Medicine",
        "year": "2016",
        "url": "https://doi.org/10.1007/s12160-016-9817-5",
        "doi": "10.1007/s12160-016-9817-5",
        "pmid": "27401000"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "研究发现",
        "paragraphs": [
          "恢复期收缩压最高与最低三分位组相比，后续高血压的调整后 OR 为 2.06（95% CI 1.19—3.57）。这是特定前瞻性关联，不是个人恢复截点。"
        ]
      },
      {
        "id": "limits",
        "title": "范围与局限",
        "paragraphs": [
          "636 名基线无高血压及心血管疾病的 Whitehall II 参与者，平均年龄 59.1 岁。",
          "暴露并非随机，残余混杂及特定队列限制因果解释。OR 不等于个人概率之比；调整变量包括基线血压。"
        ]
      },
      {
        "id": "sample",
        "title": "研究人群与样本",
        "paragraphs": [
          "636 名基线无高血压及心血管疾病的 Whitehall II 参与者，平均年龄 59.1 岁。"
        ]
      },
      {
        "id": "exposure",
        "title": "暴露或干预",
        "paragraphs": [
          "标准化心理任务的血压及纤维蛋白原反应。"
        ]
      },
      {
        "id": "outcomes",
        "title": "观察结局",
        "paragraphs": [
          "根据诊室血压与用药情况定义的新发高血压。"
        ]
      },
      {
        "id": "duration",
        "title": "时间范围",
        "paragraphs": [
          "平均八年随访。"
        ]
      },
      {
        "id": "funding",
        "title": "研究资金来源",
        "paragraphs": [
          "出版声明报告英国心脏基金会资助 RG/10/005/28296。"
        ]
      },
      {
        "id": "conflicts",
        "title": "研究利益关系",
        "paragraphs": [
          "尚未根据全文核实。"
        ]
      },
      {
        "id": "basis",
        "title": "导读范围",
        "paragraphs": [
          "查阅 UCL 托管的已发表全文：样本、表 3、恢复期三分位比较及资助声明；没有复现个人风险模型。"
        ],
        "links": [
          {
            "label": "PubMed 书目与摘要",
            "url": "https://pubmed.ncbi.nlm.nih.gov/27401000/"
          },
          {
            "label": "UCL 托管的已发表全文",
            "url": "https://discovery.ucl.ac.uk/id/eprint/1504197/1/art%253A10.1007%252Fs12160-016-9817-5.pdf"
          }
        ]
      }
    ]
  }
}