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    "type": "RDN",
    "kind": "note",
    "key": "liu-2026",
    "id": "TAP-RDN-0102",
    "locale": "en",
    "path": "/research/liu-2026/",
    "title": "TAP reading note: How the Acute Psychosocial Stress Response Ends: A Post-Stressor Transition Model of Glucocorticoid Feedback, Vagal Re-Engagement, and Frontolimbic Context Updating",
    "description": "Proposes a post-stressor transition model linking threat-context updating, cardiac vagal regulation and continuing HPA output. Distinguishes event offset, system-specific resolution and demonstrated adaptation, with testable propositions.",
    "rights": "© The Allostasis Project. All rights reserved. Reproduction or adaptation requires separate permission, subject to applicable legal exceptions.",
    "version": "1.0",
    "updatedAt": "2026-11-13",
    "editorial": {
      "contentType": "evidence-review",
      "reviewState": "draft",
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      "reviewedVersion": null,
      "updatedAt": "2026-11-13",
      "version": "1.0",
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      "author": null,
      "reviewer": null,
      "workflow": {
        "ai": {
          "usage": "used",
          "system": "OpenAI Codex",
          "scope": "Source-based research, drafting, translation and figure preparation. Access scope is stated in each source note.",
          "version": "1.0",
          "tasks": [
            "Source comparison and quantitative interpretation",
            "Bilingual synthesis and accessible figures"
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        }
      },
      "revisions": []
    },
    "original": {
      "id": "liu-2026",
      "title": "How the Acute Psychosocial Stress Response Ends: A Post-Stressor Transition Model of Glucocorticoid Feedback, Vagal Re-Engagement, and Frontolimbic Context Updating",
      "authors": "Liu C, Zheng R, Wu Y, Zhang M",
      "journal": "International journal of molecular sciences",
      "year": "2026",
      "url": "https://doi.org/10.3390/ijms27209047",
      "doi": "10.3390/ijms27209047",
      "pmid": "42941820"
    },
    "references": [
      {
        "id": "liu-2026",
        "title": "How the Acute Psychosocial Stress Response Ends: A Post-Stressor Transition Model of Glucocorticoid Feedback, Vagal Re-Engagement, and Frontolimbic Context Updating",
        "authors": "Liu C, Zheng R, Wu Y, Zhang M",
        "journal": "International journal of molecular sciences",
        "year": "2026",
        "url": "https://doi.org/10.3390/ijms27209047",
        "doi": "10.3390/ijms27209047",
        "pmid": "42941820"
      }
    ],
    "sections": [
      {
        "id": "finding",
        "title": "What the study found",
        "paragraphs": [
          "Proposes a post-stressor transition model linking threat-context updating, cardiac vagal regulation and continuing HPA output. Distinguishes event offset, system-specific resolution and demonstrated adaptation, with testable propositions."
        ]
      },
      {
        "id": "limits",
        "title": "Scope & limitations",
        "paragraphs": [
          "Structured narrative synthesis focused mainly on adult psychosocial-stress paradigms, drawing on several evidence levels.",
          "A proposed framework, not a newly discovered biological system or clinically validated score. Added model parameters require identifiable measurement, independent prediction and experimental tests."
        ]
      },
      {
        "id": "sample",
        "title": "Population & sample",
        "paragraphs": [
          "Structured narrative synthesis focused mainly on adult psychosocial-stress paradigms, drawing on several evidence levels."
        ]
      },
      {
        "id": "exposure",
        "title": "Exposure or intervention",
        "paragraphs": [
          "Post-stressor hormonal, autonomic, neural, cognitive and immune processes."
        ]
      },
      {
        "id": "outcomes",
        "title": "Outcomes",
        "paragraphs": [
          "Mechanistic hypotheses, competing explanations and measurement recommendations."
        ]
      },
      {
        "id": "duration",
        "title": "Time frame",
        "paragraphs": [
          "Published 12 October 2026; timescales depend on the system."
        ]
      },
      {
        "id": "funding",
        "title": "Research funding",
        "paragraphs": [
          "Authors report no external funding; acknowledge institutional support from Henan Provincial People’s Hospital and Sichuan Academy of Medical Sciences–Sichuan Provincial People’s Hospital."
        ]
      },
      {
        "id": "conflicts",
        "title": "Research conflicts of interest",
        "paragraphs": [
          "The authors declare no competing interests."
        ]
      },
      {
        "id": "basis",
        "title": "Reading scope",
        "paragraphs": [
          "Publisher full-text scope, model propositions, limitations and declarations. This note does not independently validate the proposed mechanisms or reassess every cited study."
        ],
        "links": [
          {
            "label": "PubMed record and abstract",
            "url": "https://pubmed.ncbi.nlm.nih.gov/42941820/"
          },
          {
            "label": "Publisher full text",
            "url": "https://www.mdpi.com/1422-0067/27/20/9047"
          }
        ]
      }
    ]
  }
}