Resilience phenotypes derived from an active inference account of allostasis
Laura A. Harrison · Antonio J. Gracias · Karl J. Friston · J. Galen Buckwalter
Frontiers in Behavioral Neuroscience · 2025
What the research tells us
Proposes an active-inference account of allostasis and four resilience phenotypes. Environment, prediction and actions that shape the environment are central to the explanation.
What to keep in mind
The proposed phenotypes are theoretical. This paper does not establish a diagnostic classifier or validate TAP’s framework.
Study at a glance
- POPULATION & SAMPLE
- Theoretical synthesis; no new validation cohort for the four phenotypes.
- EXPOSURE / INTERVENTION / SUBJECT
- Enactive allostasis and strategies for engaging with a changing environment.
- OUTCOMES
- Proposed fragile, durable, resilient and pro-entropic phenotypes.
- TIME FRAME
- No single experimental or follow-up period.
Cited on this site
Editorial & review record
Record for v0.1 · Updated
Editing & copyediting
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AI-assistedTAP Research Agent
Conceptual synthesis and source-linked educational preparation; not completed human scientific or methodological review.
OpenAI Codex (GPT-6) — Research assistance · Drafting and bilingual editing · Source-to-claim checks — Human checks have not been recorded.
v0.1
Scope of this reading note
Publisher full text and PMC full-text XML, including the article type, proposed phenotypes and funding/conflict declarations.
- STUDY FUNDING
- The authors report no financial support for the research or publication.
- STUDY CONFLICTS OF INTEREST
- The authors report no commercial or financial conflicts and disclose Frontiers editorial-board membership at submission.
Project support
Founded and supported by Resilio.
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