Impact of baseline and longitudinal allostatic load changes on incident cardiovascular disease and all-cause mortality: A 7-year population-based cohort study in China
Yachao Li · Chu Chen · Ying Wen · Xiuli Wang · Ziqian Zeng · Hongying Shi · Xiaofang Chen · Ruichan Sun · Qingping Xue
Journal of Affective Disorders · 2024
What the research tells us
In CHARLS participants aged 45 and older, higher baseline allostatic load and increases over time were associated with subsequent cardiovascular disease and all-cause mortality.
Scope & interpretation
The observational design limits causal interpretation, and cardiovascular disease was based on self-reported physician diagnosis. Findings should be interpreted within the study’s age range and follow-up conditions.
Study at a glance
- POPULATION & SAMPLE
- Analysis of the China Health and Retirement Longitudinal Study; outcome-specific sample counts are not stated in the abstract used for this note.
- EXPOSURE / INTERVENTION / SUBJECT
- Baseline allostatic load and change in AL across four years.
- OUTCOMES
- Incident cardiovascular disease and all-cause mortality assessed separately using adjusted survival models.
- TIME FRAME
- A seven-year cohort analysis, with AL change assessed over a four-year interval.
Cited on this site
Editorial & review record
Record for v0.2 · Updated
Editorial responsibility: TAP Editorial Team
Editorial note
Under the editorial responsibility of the TAP Editorial Team, this publication used AI assistance for content organization and editing.
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How responsibilities and review are recorded ↗Scope of this reading note
Selected research interpretation based on the original abstract and bibliographic record.
- Funding & competing interests
- Funding and competing-interest details have not been verified against the full text. Consult the original publication’s declarations.
Project support
Founded and supported by Resilio.
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