Allostatic load biomarkers of chronic stress and impact on health and cognition
Robert-Paul Juster · Bruce S. McEwen · Sonia J. Lupien
Neuroscience & Biobehavioral Reviews · 2010
What the research tells us
This review connects the allostatic-load framework with neuroendocrine, immune, metabolic and cardiovascular measures, illustrating why cumulative physiological risk is studied across systems.
What to keep in mind
The measures discussed differ in meaning and collection methods. A list of biomarkers is not a standardized clinical panel, and this review cannot identify the cause of an individual symptom.
Study at a glance
- POPULATION & SAMPLE
- Review of theoretical and empirical stress, health and cognition research; no single trial sample.
- EXPOSURE / INTERVENTION / SUBJECT
- Chronic stress, risk and protective factors, and multisystem biomarker indices.
- OUTCOMES
- Physical and mental health, cognition and cumulative physiological risk.
- TIME FRAME
- Literature synthesis published in 2010; time windows vary across the underlying studies.
Cited on this site
Editorial & review record
Record for v0.1 · Updated
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Scope of this reading note
Based on the original publication’s abstract and bibliographic record. This is a selected reading note, not a systematic appraisal.
- STUDY FUNDING
- Not yet checked against the full publication.
- STUDY CONFLICTS OF INTEREST
- Not yet checked against the full publication.
Project support
Founded and supported by Resilio.
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