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Low energy availability reduces myofibrillar and sarcoplasmic muscle protein synthesis in trained females

Mikkel Oxfeldt · Stuart M. Phillips · Ole Emil Andersen · Frank Ted Johansen · Maj Bangshaab · Jeyanthini Risikesan · James McKendry · Anna Katarina Melin · Mette Hansen
The Journal of Physiology · 2023

View the original source DOI: 10.1113/JP284967 ↗PubMed: 37329147 ↗

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Original paper · cite this source for the study’s findings.

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What the research tells us

Lower energy availability reduced integrated muscle protein synthesis.

Scope & interpretation

Short, controlled exposure in trained women; protein synthesis is not a whole-body recovery outcome.

Study at a glance

POPULATION & SAMPLE
30 trained, eumenorrheic women randomized.
EXPOSURE / INTERVENTION / SUBJECT
Provided diets with lower versus adequate energy availability; standardized training and matched protein provision.
OUTCOMES
Integrated myofibrillar and sarcoplasmic protein synthesis.
TIME FRAME
Ten intervention days after a five-day run-in.

Cited on this site

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Can Underfueling Affect Recovery?

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    Not yet scientifically reviewed

Editorial note

Under the editorial responsibility of the TAP Editorial Team, this publication used AI assistance for content organization and editing. Scientific review is recorded separately on this page.

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Scope of this reading note

Publisher full text and Aarhus University repository PDF, including final-page disclosures.

Study funding
Aarhus University Faculty of Health, Danish Ministry of Culture and Team Danmark; J. McKendry held a CIHR postdoctoral fellowship.
Competing interests
S. M. Phillips disclosed grants/contracts from US National Dairy Council, CIHR, Dairy Farmers of Canada, Roquette Freres, Ontario Centre of Innovation, Nestle Health Sciences, Myos, NSERC, Friesland Campina and US NIH; Nestle personal fees and Enhanced Recovery non-financial support outside this work; Exerkine-licensed patents without reported financial gains.

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Founded and supported by Resilio.

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Project informationPrivacy PolicyProject informationContactAssessmentTAP Load & Recovery ProfileMethodsLoad & Recovery Profile: Methods & DevelopmentExploreQuestions about Human AdaptationExploreMeasurement & InterpretationReading guide · Essential 35Load & Recovery: Six Research DirectionsReading guide · Essential 5Allostatic LoadReading guide · Essential 5Recovery ScienceReading guide · Essential 5Reserve & ResilienceReading guide · Essential 5MeasurementFoundationsLoadFoundationsAllostasisFoundationsRecoveryFoundationsAllostatic LoadFoundationsPhysiological ReserveFoundationsResilienceFeaturesAllostatic Load: The Hidden Cost of AdaptationFeaturesRecovery Is Not RestFeaturesWhat Is Resilience Nutrition?FeaturesModels of Adaptation: What Different Frameworks ExplainFeaturesTAP Human Adaptation FrameworkFeaturesAre Recovery and Resilience the Same Thing?FeaturesCan Underfueling Affect Recovery?FeaturesCan Weekend Catch-Up Sleep Make Up for a Week of Short Sleep?FeaturesDoes Recovery Always Mean Returning to the Same Baseline?FeaturesHow Are Physiological Reserve and Resilience Related?FeaturesWhat Can HRV Tell Us About Recovery?FeaturesWhat Counts as Evidence That Nutrition Supports Recovery?FeaturesWhat Does Your Wearable’s Recovery Score Actually Tell You?FeaturesWhen HRV Drops: Normal Variation or a Change in Recovery?FeaturesWhy Can Stress Responses Continue After Work Ends?FeaturesWhy Feeling Better Doesn’t Always Mean Fully RecoveredMethods & projectEvidence grading & methodsMethods & projectEditorial & scientific standardsMethods & projectAbout the projectResearch · 1993Stress and the individual. 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