The Reactive Scope Model — A new model integrating homeostasis, allostasis, and stress
L. Michael Romero · Molly J. Dickens · Nicole E. Cyr
Hormones and Behavior · 2009
What the research tells us
Proposes four ranges of physiological mediators: predictable regulation, responses to unexpected demands, overload and failure. The authors use changing boundaries to describe how history and context may alter an individual’s reactive scope.
What to keep in mind
The proposed ranges are not universal human cutoffs or a validated whole-body reserve scale.
Study at a glance
- POPULATION & SAMPLE
- No new cohort or intervention trial is reported in the abstract.
- EXPOSURE / INTERVENTION / SUBJECT
- Predictable and unpredictable demands; mediator levels and changing response ranges.
- OUTCOMES
- A graphical model of regulation and overload, not a clinical effect estimate.
- TIME FRAME
- Multiple timescales; no single follow-up period.
Cited on this site
Editorial & review record
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Scope of this reading note
PubMed/Europe PMC abstract and bibliographic metadata. This reading note describes the proposed model; it does not assess empirical validation across species.
- STUDY FUNDING
- The bibliographic abstract does not report funding.
- STUDY CONFLICTS OF INTEREST
- The bibliographic abstract does not report a conflict-of-interest declaration.
Project support
Founded and supported by Resilio.
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