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Impact of baseline and longitudinal allostatic load changes on incident cardiovascular disease and all-cause mortality: A 7-year population-based cohort study in China

Yachao Li · Chu Chen · Ying Wen · Xiuli Wang · Ziqian Zeng · Hongying Shi · Xiaofang Chen · Ruichan Sun · Qingping Xue
Journal of Affective Disorders · 2024

查看原始来源 DOI: 10.1016/j.jad.2024.03.124 ↗PubMed: 38548202 ↗

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这篇研究说了什么

在 CHARLS 中 45 岁及以上参与者中，较高的基线适应负荷及其随时间增加，与后续心血管疾病和全因死亡相关。

读到这里，需要注意

观察性关联不能证明降低 AL 分数就能改变风险。心血管疾病依据参与者自报的医生诊断，结果也不能自动外推到年轻人。

研究概览

研究人群与样本
中国健康与养老追踪调查分析；本导读使用的摘要未列出各结局的具体分析人数。
暴露、干预或研究对象
基线适应负荷，以及四年内 AL 的变化。
观察结局
以调整后的生存模型分别考察新发心血管疾病和全因死亡。
时间范围
七年队列分析，其中 AL 变化使用四年间隔进行评估。

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