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Impact of baseline and longitudinal allostatic load changes on incident cardiovascular disease and all-cause mortality: A 7-year population-based cohort study in China

Yachao Li · Chu Chen · Ying Wen · Xiuli Wang · Ziqian Zeng · Hongying Shi · Xiaofang Chen · Ruichan Sun · Qingping Xue
Journal of Affective Disorders · 2024

查看原始来源 DOI: 10.1016/j.jad.2024.03.124 ↗PubMed: 38548202 ↗

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这篇研究说了什么

在 CHARLS 中 45 岁及以上参与者中，较高的基线适应负荷及其随时间增加，与后续心血管疾病和全因死亡相关。

适用范围与解释

观察性设计限制因果解释，心血管疾病依据自报的医生诊断。结论应结合研究的年龄范围与随访条件理解。

研究概览

研究人群与样本
中国健康与养老追踪调查分析；本导读使用的摘要未列出各结局的具体分析人数。
暴露、干预或研究对象
基线适应负荷，以及四年内 AL 的变化。
观察结局
以调整后的生存模型分别考察新发心血管疾病和全因死亡。
时间范围
七年队列分析，其中 AL 变化使用四年间隔进行评估。

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项目信息隐私政策项目信息联系我们评估工具TAP 负荷与恢复评估方法负荷与恢复评估：方法与开发探索频道关于人体适应的科学问题探索频道测量与解释阅读指南 · 精选 35 篇负荷与恢复：六条研究线索阅读指南 · 精选 5 篇适应负荷阅读指南 · 精选 5 篇恢复科学阅读指南 · 精选 5 篇储备与复原力阅读指南 · 精选 5 篇测量与解释基础概念负荷Load基础概念动态适应Allostasis基础概念恢复Recovery基础概念适应负荷Allostatic Load基础概念生理储备Physiological Reserve基础概念复原力Resilience科学专题适应负荷如何测量？看懂生物标志物、计分方法与局限科学专题恢复，不只是休息科学专题什么是复原力营养？科学专题适应模型：不同框架分别解释什么？科学专题TAP 人体动态适应框架科学专题HRV 能告诉我们多少关于恢复的信息？科学专题HRV为什么会下降？把低读数放回测量、生活与恢复背景中科学专题为什么下班了，身体还没有“下班”？科学专题吃得不够，会影响恢复吗？科学专题周末补觉，能补回一周的睡眠不足吗？科学专题恢复一定意味着回到原来的基线吗？科学专题恢复与复原力是一回事吗？科学专题感觉好一些，为什么不一定代表已经恢复？科学专题手表上的恢复分数，到底在告诉你什么？科学专题生理储备与复原力是什么关系？科学专题营养如何影响恢复？从人体研究看机制、功能与适用边界方法与项目证据分级与评价方法方法与项目编辑与科学标准方法与项目关于项目研究文献 · 1988Muscle glycogen synthesis after exercise: effect of time of carbohydrate ingestion.研究文献 · 1993Stress and the individual. 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