TAP reading note: Allostatic load biomarkers of chronic stress and impact on health and cognition

What the study found

This review connects the allostatic-load framework with neuroendocrine, immune, metabolic and cardiovascular measures, illustrating why cumulative physiological risk is studied across systems.

Scope & limitations

Review of theoretical and empirical stress, health and cognition research; no single trial sample.

The review covers biomarkers with different meanings and collection methods. Using a panel requires specifying sampling conditions, marker selection and its relationship to the outcome of interest.

Population & sample

Review of theoretical and empirical stress, health and cognition research; no single trial sample.

Exposure or intervention

Chronic stress, risk and protective factors, and multisystem biomarker indices.

Outcomes

Physical and mental health, cognition and cumulative physiological risk.

Time frame

Literature synthesis published in 2010; time windows vary across the underlying studies.

Research funding

Not yet checked against the full publication.

Research conflicts of interest

Not yet checked against the full publication.

Reading scope

Based on the original publication’s abstract and bibliographic record. This is a selected reading note, not a systematic appraisal.

References

1. Robert-Paul Juster, Bruce S. McEwen, Sonia J. Lupien (2010). Allostatic load biomarkers of chronic stress and impact on health and cognition. Neuroscience & Biobehavioral Reviews. https://doi.org/10.1016/j.neubiorev.2009.10.002

Publication record

TAP-RDN-0013 · v0.2 · English

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