TAP reading note: Impact of baseline and longitudinal allostatic load changes on incident cardiovascular disease and all-cause mortality: A 7-year population-based cohort study in China
In CHARLS participants aged 45 and older, higher baseline allostatic load and increases over time were associated with subsequent cardiovascular disease and all-cause mortality.
Updated 2026-10-27 · Archived
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What the study found
In CHARLS participants aged 45 and older, higher baseline allostatic load and increases over time were associated with subsequent cardiovascular disease and all-cause mortality.
Scope & limitations
Analysis of the China Health and Retirement Longitudinal Study; outcome-specific sample counts are not stated in the abstract used for this note.
The observational design limits causal interpretation, and cardiovascular disease was based on self-reported physician diagnosis. Findings should be interpreted within the study’s age range and follow-up conditions.
Population & sample
Analysis of the China Health and Retirement Longitudinal Study; outcome-specific sample counts are not stated in the abstract used for this note.
Exposure or intervention
Baseline allostatic load and change in AL across four years.
Outcomes
Incident cardiovascular disease and all-cause mortality assessed separately using adjusted survival models.
Time frame
A seven-year cohort analysis, with AL change assessed over a four-year interval.
Research funding
Not yet checked against the full publication.
Research conflicts of interest
Not yet checked against the full publication.
Reading scope
Based on the original publication’s abstract and bibliographic record. This is a selected reading note, not a systematic appraisal.
References
Publication record
TAP-RDN-0031 · v0.2 · English
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Record for v0.2 · Updated
Editorial responsibility: TAP Editorial Team
Editorial note
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