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Kinetics and Interrelations of the Renin Aldosterone Response to Acute Psychosocial Stress: A Neglected Stress System

Gideon A, Sauter C, Fieres J, Berger T, Renner B, Wirtz PH
The Journal of clinical endocrinology and metabolism · 2020

View the original source DOI: 10.1210/clinem/dgz190 ↗PubMed: 31711229 ↗

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Original paper · cite this source for the study’s findings.

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What the research tells us

Table 2 first shows nonsignificant stress-group differences from baseline at 10 minutes for renin, 60 for cortisol, 90 for salivary aldosterone and 180 for plasma aldosterone. Renin later undershot baseline at 30 and 60 minutes.

Scope & interpretation

Nonsignificance does not establish equivalence, sustained return or recovery in every participant. Discrete samples do not locate exact transition times. Selected hormones and young men cannot represent whole-person recovery.

Study at a glance

POPULATION & SAMPLE
58 healthy young men randomized to TSST (34) or placebo TSST (24); salivary aldosterone subset 23/15.
EXPOSURE / INTERVENTION / SUBJECT
Social-evaluative TSST versus a placebo task.
OUTCOMES
Repeated plasma renin, plasma and salivary aldosterone, and salivary cortisol.
TIME FRAME
Aldosterone followed for up to 180 minutes; renin and cortisol to 60 minutes after task offset.

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How Is Recovery from Stress Measured?

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Editorial note

Under the editorial responsibility of the TAP Editorial Team, this publication used AI assistance for content organization and editing.

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Scope of this reading note

Published full text: participant groups, sampling schedules, Table 2, results and declarations. Figure 1 reports discrete statistical comparisons; no individual data were reconstructed.

Study funding
DFG EXC 2117–422037984; Swiss National Science Foundation PP00P1_128565/1; German Scholars Organization GSO/CZS 2; Stoll VITA foundation, all to P. H. Wirtz.
Competing interests
The authors declare no competing interests.

Project support

Founded and supported by Resilio.

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Project informationPrivacy PolicyProject informationContactAssessmentTAP Load & Recovery ProfileMethodsLoad & Recovery Profile: Methods & DevelopmentExploreQuestions about Human AdaptationExploreMeasurement & InterpretationReading guide · Essential 35Load & Recovery: Six Research DirectionsReading guide · Essential 5Allostatic LoadReading guide · Essential 5Recovery ScienceReading guide · Essential 5Reserve & ResilienceReading guide · Essential 5MeasurementFoundationsLoadFoundationsWhat Is Allostasis? Predictive Regulation and HomeostasisFoundationsRecoveryFoundationsWhat Is Allostatic Load? Meaning and MeasurementFoundationsPhysiological ReserveFoundationsResilienceFeaturesHow Is Allostatic Load Measured? 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